Determination of Strobilurin Fungicide Residues in Food by Gas Chromatography-Mass Spectrometry

A sensitive and selective method was developed for the determination of residues including azoxystrobin, dimoxystrobin, fluacrypyrim, fluoxastrobin, kersoxim-methyl, Z-metominostrobin and E-metominostrobin, orysastrobin, picoxystrobin, pyraclostrobin and trifloxystrobin in food such as fruits, vegetables, baverages, cereals, nuts, meats, egg and milk. Disparity organic solvents were used to ultrasound extract fungicide residues in variety samples. The extract was cleaned up by gel permeation chromatography purification system, and the elute solution was evaporated and re-resolution in definite volume. Determination and confirmation was made by gas chromatography-mass spectrometry at selective ions monitoring mode with external standard method. The calibration curves were good linear between area and the concentration of from 0. 05 - 5. 0 mg/kg with the correlation coefficient r more than 0. 99. The average recoveries from spiked samples at the three concentrations of 0. 01, 0. 1, 1. 0 mg/kg ranged from 60. 3% to 120. 0% with relative standard deviation ranged from 1. 5% to 13. 4%. The limits of detection were 0. 002 - 0.015 mg/kg in variesou matrixes.