Intensity-modulated arc therapy simplified

被引:60
|
作者
Wong, E
Chen, JZ
Greenland, J
机构
[1] London Reg Canc Ctr, Dept Oncol, London, ON N6A 4L6, Canada
[2] Univ Western Ontario, Dept Oncol, London, ON, Canada
[3] Univ Western Ontario, Dept Appl Math, London, ON N6A 5B9, Canada
关键词
intensity modulation; are therapy; treatment planning;
D O I
10.1016/S0360-3016(02)02735-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: We present a treatment planning strategy for intensity-modulated radiation therapy using gantry arcs with dynamic multileaf collimator, previously termed intensity-modulated are therapy (IMAT). Methods and Materials: The planning strategy is an extension of the photon bar arc and asymmetric are techniques and is classified into three levels of complexity, with increasing number of gantry arcs. This principle allows us to generalize the analysis of the number of arcs required for intensity modulation for a given treatment site. Using a phantom, we illustrate how the current technique is more flexible than the photon bar are technique. We then compare plans from our strategy with conventional three-dimensional conformal treatment plans for three sites: prostate (prostate plus seminal vesicles), posterior pharyngeal wall, and chest wall. Results: Our strategy generates superior IMAT treatment plans compared to conventional three-dimensional conformal plans. The IMAT plans spare critical organs well, and the trade-off for simplicity is that the dose uniformity in the target volume may not rival that of true inverse treatment plans. Conclusions: The analyses presented in this paper give a better understanding of IMAT plans. Our strategy is easier to understand and more efficient in generating plans than inverse planning systems; our plans are also simpler to modify, and quality assurance is more intuitive. (C) 2002 Elsevier Science Inc.
引用
收藏
页码:222 / 235
页数:14
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