Asymmetric synthesis of the Abbott amino dihydroxyethylene dipeptide isostere subunit

被引：10
|
作者：
Haddad, M
Larcheveque, M
机构：
[1] Lab. de Synt. Organique Associe, ENSCP, 75231 Paris Cedex 05
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 26期
关键词：
D O I：
10.1016/0040-4039(96)00874-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The aminodiol 1b, a N-benzyl protected form of the Abbott dipeptide isostere la is prepared, starling from an appropriate alpha,beta-unsaturated ester, involving an asymmetric dihydroxylation and a rearrangement of an intermediate anti alpha,beta-aminoepoxide. Copyright (C) 1996 Published by Elsevier Science Ltd
引用
收藏
页码：4525 / 4528
页数：4
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