Solid-phase synthesis of α,α-difluoro-β-amino acids via the Reformatsky reaction

被引：34
|
作者：
Vidal, A [1 ]
Nefzi, A [1 ]
Houghten, RA [1 ]
机构：
[1] Torrey Pines Inst Mol Studies, San Diego, CA 92121 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 24期
关键词：
D O I：
10.1021/jo010872z
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：8268 / 8272
页数：5
相关论文
共 50 条
  • [1] Solid phase synthesis of α,α-difluoro-β-amino acid derivatives by Reformatsky reaction.
    Vidal, A
    Vidal, A
    Nefzi, A
    Nefzi, A
    Houghten, RA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 223 : U556 - U556
  • [2] Solid phase synthesis of α,α-difluoro-β-amino acid derivatives by reformatsky reaction.
    Vidal, A
    Nefzi, A
    Houghten, RA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 223 : B209 - B209
  • [3] Solid-phase synthesis of α,α-difluorinated β-amino acids by Reformatsky reaction
    Nefzi, A
    Vidal, A
    Houghten, RA
    BIOPOLYMERS, 2003, 71 (03) : 353 - 353
  • [4] The Mitsunobu reaction in the synthesis of α,α-difluoro-β-amino acids
    Fokina, NA
    Kornilov, AM
    Kukhar, VP
    JOURNAL OF FLUORINE CHEMISTRY, 2001, 111 (01) : 69 - 76
  • [5] Diastereoselective Synthesis of Aliphatic α,α-Difluoro-β3-Amino Esters via a Sonocatalyzed Reformatsky Reaction
    March, Taryn L.
    Johnston, Martin R.
    Duggan, Peter J.
    ORGANIC LETTERS, 2012, 14 (01) : 182 - 185
  • [6] α,β-Difluoro-γ- amino acids Synthesis and applications
    Hunter, Luke
    CHIMICA OGGI-CHEMISTRY TODAY, 2012, 30 (03) : 20 - 22
  • [7] An expedient synthesis of α,α-difluoro-β-hydroxy ketones via decarboxylative aldol reaction of α,α-difluoro-β-keto acids with aldehydes
    Huang, Da-Kang
    Lei, Zhong-Liang
    Zhu, Yu-Jun
    Liu, Zhen-Jiang
    Hu, Xiao-Jun
    Mao, Hai-Fang
    TETRAHEDRON LETTERS, 2017, 58 (34) : 3394 - 3397
  • [8] Convenient asymmetric synthesis off β-substituted α,α-difluoro-β-amino acids via Reformatsky reaction between Davis' N-sulfinylimines and ethyl bromodifluoroacetate
    Sorochinsky, A
    Voloshin, N
    Markovsky, A
    Belik, M
    Yasuda, N
    Uekusa, H
    Ono, T
    Berbasov, DO
    Soloshonok, VA
    JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (19): : 7448 - 7454
  • [9] The diastereoselective synthesis of difluoro-β-lactam using Reformatsky-Honda reaction
    Tarui, Atsushi
    Kondo, Keigo
    Taira, Hiroko
    Sato, Kazuyuki
    Omote, Masaaki
    Kumadaki, Itsumaro
    Ando, Akira
    HETEROCYCLES, 2007, 73 (01) : 203 - +
  • [10] Synthesis of difluorinated pseudopeptides using chiral α,α-difluoro-β-amino acids in the Ugi reaction
    Gouge, V
    Jubault, P
    Quirion, JC
    TETRAHEDRON LETTERS, 2004, 45 (04) : 773 - 776
12345