Racial Disparities in Access to Pediatric Kidney Transplantation Since Share 35

被引:61
|
作者
Amaral, Sandra [1 ]
Patzer, Rachel E. [2 ,3 ]
Kutner, Nancy [4 ]
McClellan, William [3 ,5 ]
机构
[1] Childrens Hosp Philadelphia, Dept Pediat, Philadelphia, PA 19104 USA
[2] Emory Univ, Dept Surg, Emory Transplant Ctr, Atlanta, GA 30322 USA
[3] Emory Univ, Rollins Sch Publ Hlth, Dept Epidemiol, Atlanta, GA 30322 USA
[4] Emory Univ, Dept Rehabil Med, Atlanta, GA 30322 USA
[5] Emory Univ, Dept Med, Atlanta, GA 30322 USA
来源
关键词
STAGE RENAL-DISEASE; UNITED-STATES; ADOLESCENTS; CHILDREN; HOSPITALIZATION; HEMODIALYSIS; ASSOCIATION; MORTALITY; SURVIVAL; OUTCOMES;
D O I
10.1681/ASN.2011121145
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Share 35 was enacted in 2005 to shorten transplant wait times and provide high-quality donors to children with ESRD. To investigate the possible effect of this policy on racial disparities in access to pediatric transplantation, we analyzed data from the US Renal Data System before and after Share 35. Among 4766 pediatric patients with incident ESRD, the probability of receiving a deceased-donor kidney transplant increased 46% after Share 35, with Hispanics experiencing the greatest improvements (increases of 81% for Hispanics, 45% for blacks, and 37% for whites). On average, patients received a deceased-donor kidney transplant earlier after Share 35, but this finding varied by race: 63 days earlier for whites, 90 days earlier for blacks, and 201 days earlier for Hispanics. Furthermore, a shift from living- to deceased-donor sources occurred with Share 35 for all races, with a 25% reduction in living donors for whites compared with 48% and 46% reductions for Hispanics and blacks, respectively. In summary, Share 35 seems to have attenuated racial disparities in the time to and probability of children receiving a deceased-donor kidney transplant. These changes coincided with changes in the rates of living-donor sources, which vary by race. Future studies should explore how these changes may impact racial differences in long-term graft outcomes.
引用
收藏
页码:1069 / 1077
页数:9
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