A Review on the Recent Trend in Osteoporosis Highly Cited Papers

The goal of this study was to compile the list of highly cited papers in osteoporosis across Web of Science Clarivate Analytics to identify current trends in osteoporosis research. We searched the Web of Science on 18 February 2021 with a search strategy including osteoporosis and all its related keywords. Search results were limited to the highly cited papers published in the last 5 years (2016-2020). Our search strategy on the Web of Science database retrieved 94 highly cited papers, related to osteoporosis. Out of 94 included papers, the biggest portion was secondary studies (44.7%) followed by animals/preclinical studies (31.9%) and primary studies (23.4%). These papers received 12,748 citations with the average 135.6 citations per paper. The main focus of highly cited clinical studies was on interventions (mostly RCTs on newly approved anabolic agents, and on the rebound in vertebral fractures after denosumab discontinuation), followed by topics on risk assessment and epidemiology. The highly cited papers in osteoporosis tend to be secondary studies carried out in the USA with US governmental institutions and pharmaceutical companies grants. These papers reflect several hot topics in osteoporosis including RCTs on anabolic agents during the last 5 years.