ANAEMIA The safety and efficacy of peginesatide in patients with CKD

被引：16
|
作者：
Eckardt, Kai-Uwe [1 ]
机构：
[1] Univ Erlangen Nurnberg, Dept Hypertens & Nephrol, D-91054 Erlangen, Germany
来源：
NATURE REVIEWS NEPHROLOGY | 2013年 / 9卷 / 04期
关键词：
CHRONIC KIDNEY-DISEASE; ALPHA;
D O I：
10.1038/nrneph.2013.42
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Recently published data from four phase 3 safety and efficacy trials show that the synthetic peptide-based, erythropoietin mimetic, peginesatide, is noninferior to conventional erythropoiesis-stimulating agents in increasing haemoglobin levels in patients with chronic kidney disease (CKD). However, peginesatide therapy increased the risk of a combined cardiovascular end point in patients with CKD not on dialysis. Eckardt, K.-U. Nat. Rev. Nephrol. 9, 192-193 (2013); published online 12 March 2013; doi:10.1038/nrneph.2013.42
引用
收藏
页码：192 / 193
页数：3
相关论文
共 50 条
  • [1] The safety and efficacy of peginesatide in patients with CKD
    Kai-Uwe Eckardt
    Nature Reviews Nephrology, 2013, 9 : 192 - 193
  • [2] IMPACT OF DIABETES ON SAFETY AND EFFICACY OF PEGINESATIDE IN HEMODIALYSIS PATIENTS
    Spinowitz, Bruce
    Zabaneh, Raja
    Martin, Edouard
    Mehta, Bhasker Rai
    Yan, Jieshi
    Yang, Alex
    Chen, Minjia
    Tang, Helen
    Cooper, Dan
    Polu, Krishna
    Schiller, Brigitte
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2012, 59 (04) : A80 - A80
  • [3] EFFICACY AND SAFETY OF PEGINESATIDE IN JAPANESE CHRONIC KIDNEY DISEASE PATIENTS ON HEMODIALYSIS
    Saito, Akira
    Saito, Akira
    Tsubakihara, Yoshiharu
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2012, 27 : 136 - 136
  • [4] EFFICACY AND SAFETY OF PEGINESATIDE IN JAPANESE CHRONIC KIDNEY DISEASE PATIENTS NOT ON DIALYSIS
    Tsubakihara, Yoshiharu
    Tsubakihara, Yoshiharu
    Saito, Akira
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2012, 27 : 136 - 136
  • [5] On Peginesatide and Anemia Treatment in CKD
    Parfrey, Patrick S.
    Warden, Geoff
    Barrett, Brendan J.
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2013, 62 (04) : 659 - 661
  • [6] SAFETY AND EFFICACY OF PEGINESATIDE FOR TREATMENT OF ANEMIA IN HEMODIALYSIS PATIENTS PREVIOUSLY ON EPOETIN ALFA
    Schiller, Brigitte
    Zeig, Steven
    Hura, Claudia
    Levin, Nathan
    Kaplan, Mark
    Tang, Hong
    Mayo, Martha
    Polu, Krishna
    Duliege, Anne-Marie
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2011, 57 (04) : A85 - A85
  • [7] SAFETY AND EFFICACY OF PEGINESATIDE FOR TREATMENT OF ANEMIA IN HEMODIALYSIS PATIENTS PREVIOUSLY ON EPOETIN ALFA OR BETA
    Besarab, Anatole
    Locatelli, Francesco
    Covic, Adrian
    Martin, Edouard
    Bernardo, Maraliza
    Macdougall, Iain
    Tang, Hong
    Mayo, Martha
    Polu, Krishna
    Duliege, Anne-Marie
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2011, 57 (04) : A25 - A25
  • [8] SAFETY AND EFFICACY OF FEBUXOSTAT IN ADVANCED CKD PATIENTS WITH HYPERURICEMIA
    Oh, Y-J.
    Park, E. S.
    Ahn, S. S.
    Lee, K. Y.
    Byun, S-J.
    Pyo, J. Y.
    Jung, S. M.
    Lee, S-W.
    Park, Y-B.
    Song, J. J.
    ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 383 - 384
  • [9] Safety and Efficacy of Febuxostat in Advanced CKD Patients with Hyperuricemia
    Oh, Yoon-Jeong
    Jung, Seung Min
    Lee, Sang-Won
    Park, Yong-Beom
    Song, Jason Jungsik
    ARTHRITIS & RHEUMATOLOGY, 2016, 68
  • [10] Efficacy and Safety of Sotagliflozin in Patients with Type 1 Diabetes and CKD
    Sridhar, Vikas S.
    Odutayo, Ayodele
    Garg, Satish
    Danne, Thomas
    Doria, Alessandro
    Mauer, Michael
    Davies, Michael J.
    Banks, Phillip
    Girard, Manon
    Cherney, David Z. I.
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2024,
12345