Adenocarcinoma (Not Otherwise Specified) of the Major Salivary Glands

The objective of this study was to report our experience with managing primary adenocarcinoma, not otherwise specified (NOS), of the major salivary glands. Adenocarcinoma (NOS) of the major salivary glands is an uncommon disease that usually presents as a high grade lesion at an advanced stage. Although surgical resection followed by radiotherapy has been the mainstay of treatment for this disease in the absence of distant metastases, disease recurrence/persistence is still quite common. Our study demonstrates that concurrent chemotherapy (cisplatin) and radiotherapy after previous surgery may improve disease control and warrants consideration and further investigation.