Nanostructured Hydroxyapatite Microspheres by Templated Synthesis: Formation and Mechanisms

被引:1
|
作者
Xiao Dong-Qin [1 ]
Chi Feng [1 ]
Yao Ning [1 ]
Zhang Cheng-Dong [1 ]
Duan Ke [1 ]
Weng Jie [1 ]
机构
[1] Southwest Jiaotong Univ, Sch Mat Sci & Engn, Key Lab Adv Technol Mat, Chengdu 610031, Peoples R China
基金
中国国家自然科学基金;
关键词
hydroxyapatite; template; microspheres; nanostructure; self-assemble; CALCIUM-PHOSPHATE NANOSPHERES; SPHERICAL NANO-HYDROXYAPATITE; BLOCK-COPOLYMER MICELLE; BIOMIMETIC SYNTHESIS; HYDROTHERMAL SYNTHESIS; FACILE PREPARATION; HOLLOW; FABRICATION; GROWTH; SIZE;
D O I
10.3724/SP.J.1206.2013.00285
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
As a main inorganic component of the human bone, hydroxyapatite (HA) is widely used in hard tissue repair and replacement. With high surface area and excellent fluidity, HA microspheres have gained extensive interests for biomedical applications. This article reviews the synthesis of HA microspheres with nanostructures, with a special focus on the use of soft and hard templates. The formation mechanism of these microspheres and related nanostructures are also discussed in detail. Problems in current synthesis methods are identified and the future trends of this emerging field are also discussed.
引用
收藏
页码:935 / 947
页数:13
相关论文
共 72 条
  • [1] Adsorption of succinylated lysozyme on hydroxyapatite
    Barroug, A
    Fastrez, J
    Lemaitre, J
    Rouxhet, P
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1997, 189 (01) : 37 - 42
  • [2] A block copolymer micelle template for synthesis of hollow calcium phosphate nanospheres with excellent biocompatibility
    Bastakoti, Bishnu Prasad
    Inuoe, Masamichi
    Yusa, Shin-ichi
    Liao, Shih-Hsiang
    Wu, Kevin C. -W.
    Nakashima, Kenichi
    Yamauchi, Yusuke
    [J]. CHEMICAL COMMUNICATIONS, 2012, 48 (52) : 6532 - 6534
  • [3] Controlled release of bovine serum albumin from hydroxyapatite microspheres for protein delivery system
    Boonsongrit, Yaowalak
    Abe, Hiroya
    Sato, Kazuyoshi
    Naito, Makio
    Yoshimura, Masahiro
    Ichikawa, Hideki
    Fukumori, Yoshinobu
    [J]. MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS, 2008, 148 (1-3): : 162 - 165
  • [4] Synthesis of hydroxyapatite nanopowders via sucrose-templated sol-gel method
    Bose, S
    Saha, SK
    [J]. JOURNAL OF THE AMERICAN CERAMIC SOCIETY, 2003, 86 (06) : 1055 - 1057
  • [5] Ultrasonic controlled morphology transformation of hollow calcium phosphate nanospheres: A smart and biocompatible drug release system
    Cai, Yurong
    Pan, Haihua
    Xu, Xurong
    Hu, Qinghong
    Li, Ling
    Tang, Ruikang
    [J]. CHEMISTRY OF MATERIALS, 2007, 19 (13) : 3081 - 3083
  • [6] [陈景帝 CHEN Jingdi], 2007, [材料科学与工艺, Material Science and Technology], V15, P515
  • [7] Self-Assembled Growth and Pore Size Control of the Bubble-Template Porous Carbonated Hydroxyapatite Microsphere
    Cheng, Xiaokun
    Huang, Zhiliang
    Li, Jianqiu
    Liu, Yu
    Chen, Changlian
    Chi, Ru-an
    Hu, Yuehua
    [J]. CRYSTAL GROWTH & DESIGN, 2010, 10 (03) : 1180 - 1188
  • [8] Control of Pore Size of the Bubble-Template Porous Carbonated Hydroxyapatite Microsphere by Adjustable Pressure
    Cheng, Xiaokun
    He, Qianjun
    Li, Jianqiu
    Huang, Zhiliang
    Chi, Ru-an
    [J]. CRYSTAL GROWTH & DESIGN, 2009, 9 (06) : 2770 - 2775
  • [9] Synthesis of nano-sized biphasic calcium phosphate ceramics with spherical shape by flame spray pyrolysis
    Cho, Jung Sang
    Ko, You Na
    Koo, Hye Young
    Kang, Yun Chan
    [J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2010, 21 (04) : 1143 - 1149
  • [10] Copper and zinc decontamination from single- and binary-metal solutions using hydroxyapatite
    Corami, Alessia
    Mignardi, Silvano
    Ferrini, Vincenzo
    [J]. JOURNAL OF HAZARDOUS MATERIALS, 2007, 146 (1-2) : 164 - 170