How Does Functional Constipation Affect Growth Status in Children?

Background: There are some evidences suggesting functional constipation-related growth retardation in children, especially in early childhood. Considering high prevalence of constipation, early diagnosis and treatment of constipated patients may improve the quality of life in these children. In this study, weight and height of Iranian children aged 2 to 12 years with functional constipation was evaluated compared to healthy children. Methods: A total of 130 Iranian children aged 2 -12 years, 65 with functional constipation and 65 as healthy children referred to pediatric gastroenterology clinic during Jan to Dec of 2016, were enrolled in this case-control study. Functional constipation was defined as Rome III criteria. The growth status was evaluated using the growth charts, and Z scores of weight and height for age were recorded, with the consent of parents and child willingness. Results: 65 constipated patients (44 boys, 21 girls) with the mean age of 8.28 +/- 3.24 years and 65 healthy children (25 boys, 40 girls) with the mean age of 8.32 +/- 3.42 years were evaluated. The mean weight of case group was 23.69 +/- 4.14 kg and mean height 126.49 +/- 10.34 cm. The mean weight of control group with 31.62 +/- 4.85 kg and mean height 153.47 +/- 13.88 cm, demonstrated significant difference with the case group. The observed mean weight and height were significantly lower in constipated group and the differences of height-for-age and weight-for-age Z scores were statistically meaningful in constipated and healthy children. Conclusions: Functional constipation in children aged 2 to 12 years may retard their weight and height growth, so early diagnosis and treatment of children with constipation is beneficial in their adequate growth status.