Pincer deformity does not lead to osteoarthritis of the hip whereas acetabular dysplasia does: acetabular coverage and development of osteoarthritis in a nationwide prospective cohort study (CHECK)

被引:132
|
作者
Agricola, R. [1 ]
Heijboer, M. P. [1 ]
Roze, R. H. [1 ]
Reijman, M. [1 ]
Bierma-Zeinstra, S. M. A. [1 ,2 ]
Verhaar, J. A. N. [1 ]
Weinans, H. [1 ,3 ,4 ]
Waarsing, J. H. [1 ]
机构
[1] Erasmus MC Univ Med Ctr, Dept Orthopaed, Rotterdam, Netherlands
[2] Erasmus MC Univ Med Ctr, Dept Gen Practice, Rotterdam, Netherlands
[3] Delft Univ Technol, Dept Biomech Engn, Delft, Netherlands
[4] Univ Med Ctr Utrecht, Dept Orthopaed & Rheumatol, Utrecht, Netherlands
关键词
Osteoarthritis; Hip joint; Femoroacetabular impingement; Pincer impingement; Acetabular dysplasia; Risk factor; FEMOROACETABULAR IMPINGEMENT; STRUCTURAL ABNORMALITIES; COXA PROFUNDA; RISK-FACTORS; JOINT; SHAPE; ASSOCIATION; PROGRESSION; CARTILAGE; PREDICT;
D O I
10.1016/j.joca.2013.07.004
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Objective: Determining the relation between acetabular coverage, especially overcoverage which may lead to pincer impingement, and development of osteoarthritis (OA) of the hip. Design: From a prospective cohort study of 1,002 individuals with symptoms of early OA (Cohort Hip and Cohort Knee, CHECK), 720 participants were included. Standardized anteroposterior pelvic radiographs and false profile lateral radiographs were obtained at baseline and 5 years follow-up. Acetabular undercoverage (mild dysplasia) and overcoverage (pincer deformity) were measured by a centre edge angle of <25 degrees and >40 degrees respectively in both radiographic views. The strength of association between those parameters at baseline and development of incident OA (Kellgren and Lawrence (K&L) grade >2 or total hip replacement), or joint space narrowing within 5 years was expressed in odds ratio (OR) adjusted for K&L grade, age, body mass index (BMI), and sex using generalized estimating equations. Results: At baseline, 76% of the included hips had no signs of radiographic OA (K&L = 0) whereas 24% had doubtful OA (K&L = 1). Within 5 years, 7.0% developed incident OA. Acetabular dysplasia was significantly associated with development of incident OA with ORs between 2.62 (95% confidence interval (CI) 1.44-4.77) and 5.45 (95% CI 2.40-12.34), dependent on the radiographic view. A pincer deformity was not associated with any outcome measure, except for a significantly protective effect on incident OA when a pincer deformity was present in both radiographic views OR 0.34 (95% CI 0.13-0.87). Conclusion: Acetabular dysplasia was significantly associated with development of OA. However, a pincer deformity was not associated with OA, and might even have a protective effect on its development, which questions the supposed detrimental effect of pincer impingement. (C) 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:1514 / 1521
页数:8
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