Synthesis of protected dithiol amino acids for potential use in peptide chemistry

被引：2

作者：

Sun, Yong ^{[1
]}

Li, Xiang-Qin ^{[1
]}

Meng, Yun-Ping ^{[2
]}

Wang, Chao ^{[1
]}

机构：

[1] Peking Univ, Sch Pharmaceut Sci, Dept Med Chem, Beijing 100083, Peoples R China

[2] Beijing Union Univ, Biochem Engn Coll, Beijing, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2008年 / 38卷 / 19期

关键词：

amino acid; 1,3-dithiols; Mitsunobu reaction;

D O I：

10.1080/00397910802136631

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two N-Fmoc and S,S'-protected alpha-amino acids were synthesized by introducing the derivatives of dithioether into a Tyrosine side chain under the Mitsunobu protocol using the diisopropylazodicarboxylate/triphenylphosphine (DIAD/TPP) system. These amino acids provide a potential use in peptide chemistry.

引用

页码：3303 / 3310

页数：8

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