Piezoresistivity (change of the volume electrical resistivity with strain) in continuous carbon fiber polymer-matrix structural composites allows electrical-resistance-based strain/stress sensing. Uniaxial through-thickness compression is encountered in fastening. As shown for a 24-lamina quasi-isotropic epoxy-matrix composite, compression results in (i) strain-induced reversible decreases in through-thickness and longitudinal volume resistivities, due to increase in the degree of through-thickness fiber-fiber contact, and (ii) minor-damage-induced irreversible changes in these resistivities, due to a microstructural change involving an irreversible through-thickness resistivity increase and an irreversible longitudinal resistivity decrease. The Poisson effect plays a minor role. The effects in the longitudinal resistivity are small compared to those in the through-thickness direction, but longitudinal resistance measurement is more practical. The through-thickness gage factor (reversible fractional change in resistance per unit strain) ranges from 2.6 to 5.1 and the reversible fractional change in through-thickness resistivity per unit through-thickness strain ranges from 1.5 to 4.0, both quantities decreasing with increasing strain magnitude from 0.19% to 0.73% due to the increasing irreversible effect. The irreversible fractional change in through-thickness resistivity per unit through-thickness strain ranges from -1.0 to -1.3 and is strain independent. The effects are consistent with the surface resistance changes previously reported for the same material under flexure. (C) 2013 Elsevier Ltd. All rights reserved.