Objective: This study was conducted to evaluate patient satisfaction and its related factors. Designs: A cross-sectional design was used in this study. Setting and Participants: Sample size was determined as 390 from 3900 by randomized sampling in several phases according to the proportion of hospitalized and out-patient. Participants were interviewed privately face to face in the hospital time. The scale developed by Ercan et. Al in order to measure patient satisfaction in associations that are in secondary health-care services include components evaluating clinical-policlinical health care services, staff, patient-rights, hospital appearance, cafeteria services. Results: Over 25% of the participants (n=105) were in age group 29-39 years and 64.4% were female. Mean age was 38.95 +/- 8.95. Patient satisfaction differentiates according to socioeconomic, demographic, functional conditions and health. There were the significant among satisfied with patients' with hospitalized, personal relationship, patients' rights and general physical structure of the a large university hospital in Izmir, Turkey. Conclusions: The majority of out-patients were quite satisfied, with their satisfaction include mostly time related with laboratory, radiology services and bureaucratic procedures and cleanliness, hygiene, physical conditions, prices and service quality of cafeteria and quality and amount of the food given to the patients, behavior of the staff.