A multicenter randomized controlled trial for bright light therapy in adults with intellectual disabilities and depression: Study protocol and obstacle management

被引：7
|
作者：
Hamers, Pauline C. M. [1 ,2 ]
Evenhuis, Heleen M. [1 ]
Hermans, Heidi [1 ,2 ]
机构：
[1] Erasmus Univ, Med Ctr, Dept Gen Practice, Intellectual Disabil Med, POB 2040, NL-3000 CA Rotterdam, Netherlands
[2] Amarant Grp, Healthcare Org People Intellectual Disabil, Tilburg, Netherlands
来源：
RESEARCH IN DEVELOPMENTAL DISABILITIES | 2017年 / 60卷
关键词：
Bright light therapy; Depression; Intellectual disabilities; Randomized controlled trial; Circadian sleep-wake rhythm; Melatonin; Cortisol and stress; ABERRANT-BEHAVIOR-CHECKLIST; SEASONAL AFFECTIVE-DISORDER; NEGATIVE AIR IONS; OLDER-ADULTS; NONSEASONAL DEPRESSION; RHYTHM DISTURBANCES; SLEEP DISTURBANCES; CIRCADIAN-RHYTHMS; HAIR CORTISOL; DOUBLE-BLIND;
D O I：
10.1016/j.ridd.2016.10.012
中图分类号：
G76 [特殊教育];
学科分类号：
040109 ;
摘要：
Due to the limited cognitive and communicative abilities of adults with intellectual disabilities (ID), current treatment options for depression are often limited to lifestyle changes and pharmacological treatment. Bright light therapy (BLT) is an effective intervention for both seasonal and non-seasonal depression in the general population. BLT is an inexpensive, easy to carry out intervention with minimal side effects. However, knowledge on its anti-depressant effect in adults with ID is lacking. Obstacles in realizing a controlled intervention study in this particular study population may have contributed to this lack. To study the effect of BLT on depression in this population, it is necessary to successfully execute a multicenter randomized controlled trial (RCT). Therefore, the study protocol and the management of anticipated obstacles regarding this trial are presented. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：96 / 106
页数：11
相关论文
共 50 条
  • [1] A Multicenter Randomized Controlled Trial for Bright Light Therapy in Adults with Intellectual Disability and Depression: Study Protocol
    Hamers, Pauline C. M.
    Evenhuis, Heleen M.
    Hermans, Heidi
    NEUROPSYCHOBIOLOGY, 2016, 74 (04) : 238 - 239
  • [2] A Multicenter Randomized Controlled Trial for Bright Light Therapy in Adults With Intellectual Disability and Depression: Obstacles and Challenges
    Hamers, Pauline C. M.
    Evenhuis, Heleen M.
    Hermans, Heidi
    JOURNAL OF MENTAL HEALTH RESEARCH IN INTELLECTUAL DISABILITIES, 2017, 10 : 157 - 158
  • [3] A multi-centre randomised controlled trial for bright light therapy in adults with intellectual disabilities and depression
    Hamers, P.
    Evenhuis, H.
    Festen, D.
    Hermans, H.
    JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2016, 60 (7-8) : 676 - 676
  • [4] The effect of bright light therapy on depressive symptoms in adults with intellectual disabilities: Results of a multicentre randomized controlled trial
    Hamers, Pauline C. M.
    Festen, Dederieke A. M.
    Bindels, Patrick J. E.
    Hermans, Heidi
    JOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES, 2020, 33 (06) : 1428 - 1439
  • [5] A Multicenter Randomised Controlled Trial with Bright Light Therapy to Decrease Depressive Symptoms in Adults with Intellectual Disabilities: Preliminary Results
    Hamers, Pauline C. M.
    Festen, Dederieke A. M.
    Hermans, Heidi
    NEUROPSYCHOBIOLOGY, 2018, 76 (01) : 18 - 19
  • [6] The Applicability of Bright Light Therapy in Adults With Intellectual Disabilities
    Hermans, Heidi
    Soerokromo, Natascha S.
    Evenhuis, Heleen M.
    JOURNAL OF MENTAL HEALTH RESEARCH IN INTELLECTUAL DISABILITIES, 2017, 10 : 157 - 157
  • [7] A multicentre randomised controlled trial for bright light therapy in adults with intellectual disabilities and depressive symptoms: first results
    Hamers, P.
    Festen, D.
    Hermans, H.
    JOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES, 2018, 31 (04) : 557 - 558
  • [8] Bright light therapy for depression in Parkinson disease A randomized controlled trial
    Rutten, Sonja
    Vriend, Chris
    Smit, Jan H.
    Berendse, Henk W.
    van Someren, Eus J. W.
    Hoogendoorn, Adriaan W.
    Twisk, Jos W. R.
    van der Werf, Ysbrand D.
    van den Heuvel, Odile A.
    NEUROLOGY, 2019, 92 (11) : E1145 - E1156
  • [9] Adolescent depression: Study protocol for a randomized, controlled, double-blind multicenter parallel group trial of Bright Light Therapy in a naturalistic inpatient setting (DeLight)
    Martin Holtmann
    Laura Mokros
    Inken Kirschbaum-Lesch
    Michael Kölch
    Paul L. Plener
    Christian Ruckes
    Michael Schulte-Markwort
    Tanja Legenbauer
    Trials, 19
  • [10] Adolescent depression: Study protocol for a randomized, controlled, double-blind multicenter parallel group trial of Bright Light Therapy in a naturalistic inpatient setting (DeLight)
    Holtmann, Martin
    Mokros, Laura
    Kirschbaum-Lesch, Inken
    Koelch, Michael
    Plener, Paul L.
    Ruckes, Christian
    Schulte-Markwort, Michael
    Legenbauer, Tanja
    TRIALS, 2018, 19
12345