Synthesis and Antimicrobial Activity of 4H, 4-Thio-2-hepta-O-benzoyl-β-D-lactosylimino-3-phenyl-2,3-dihydro-(1,3,5)-triazino-(2,1b) 6, 7 or 8-Aryl benzothiozoles (hydrochlorides)

被引:1
|
作者
Heda, K. M. [1 ]
Deshmukh, S. P. [1 ]
机构
[1] Shri Shivaji Coll, PG Dept Chem, Akola 444001, India
关键词
Benzothiazoles; N-phenyl isocyanodichloride; 1,3,5-Triazino compounds; BIOLOGICAL-ACTIVITY; SCHIFF-BASES; DERIVATIVES; BENZOTHIAZOLES; AGENTS;
D O I
10.14233/ajchem.2013.14231
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of novel 4H, 4-thio-2-hepta-O-benzoyl-beta-D-lactosylimino-3-phenyl-2,3-dihydro-(1,3,5)-triazino-(2,1b) 6,7 or 8 aryl benzothiozoles (hydrochlorides) have been synthesized by the interaction of several 1-hepta-O-benzoyl-beta-D-lactosyl-3-aryl benzothiozolyl thiocarbamides with N-phenyl isocyanodichloride. These compounds were screened for their antibacterial and antifungal activities against-Escherichia coli, Proteus vulgaris, Staphylococcus aureus, Salmonella typhimurium, Klebsiella pneumonie, Psudomonas aeruginosa, Aspergillus niger and Candida albicance. The newly synthesized compounds have been characterized by analytical and IR, H-1 NMR and mass spectral studies.
引用
收藏
页码:5367 / 5369
页数:3
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