Monoterpene glycosides from Indigofera hetrantha

被引:3
|
作者
Mehmood, Sajid [1 ]
Aziz-Ur-Rahman [2 ]
Ahmad, Zaheer [3 ]
Afza, Nighat [1 ]
Malik, Abdul [2 ]
Ahmad, Habib [4 ]
Choudhary, Muhammad Iqbal [2 ]
机构
[1] PCSIR Labs Karachi Complex, Pharmaceut Res Ctr, Karachi 75280, Pakistan
[2] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan
[3] Univ Karachi, Dept Chem, Karachi 75270, Pakistan
[4] Govt Postgrad Jahanzeb Coll, Dept Bot, Saidu Sharif, Pakistan
关键词
Indigofera hetrantha; Leguminosae; Monoterpene glycosides; Lipoxygenase inhibition;
D O I
10.1080/14786410801980097
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Monoterpene glycosides have been isolated from the ethyl acetate soluble fraction of Indigofera hetrantha and their structures assigned to be 3,7-dimethyl-2(E),6-octadien-5-one-1-O-beta-D-6-O-acetylglucopyranoside (1) and 3,7-dimethyl-2(E), 6-octadien-5-one-1-O-[-beta-D-6"-O-acetylglucopyra-nosyl (1" -> 6')-beta-D-glucopyranoside] (2), on the basis of spectroscopic analysis including 1D and 2D NMR techniques. Compounds 1 and 2 displayed moderate inhibitory potential against the enzyme lipoxygenase.
引用
收藏
页码:1189 / 1195
页数:7
相关论文
共 50 条
  • [1] Lipoxygenase inhibiting constituents from Indigofera hetrantha
    Aziz-ur-rehman
    Malik, A
    Riaz, N
    Ahmad, H
    Nawaz, SA
    Choudhary, MI
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2005, 53 (03) : 263 - 266
  • [2] Lipoxygenase inhibiting flavonoids from Indigofera hetrantha
    Aziz-ur-Rehman
    Malik, A
    Riaz, N
    Ahmad, H
    Nawaz, SA
    Choudhary, ML
    HETEROCYCLES, 2004, 63 (02) : 359 - 366
  • [3] Phytochemical studies on Indigofera hetrantha
    Rehman, A
    Malik, A
    Mehmood, S
    Jahan, E
    Ahmad, H
    JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 2005, 27 (04): : 440 - 442
  • [4] FLAVONOIDS AND OTHER CONSTITUENTS OF INDIGOFERA-HETRANTHA
    THUSOO, A
    RAINA, N
    AHMED, SR
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1982, 59 (08) : 1007 - 1008
  • [5] FLAVONOID GLYCOSIDES FROM INDIGOFERA-HEBEPETALA
    HASAN, A
    FARMAN, M
    AHMED, I
    PHYTOCHEMISTRY, 1994, 35 (01) : 275 - 276
  • [6] Flavonol glycosides from the leaves of Indigofera zollingeriana
    Hisaeda, Aya
    Matsunami, Katsuyoshi
    Otsuka, Hideaki
    Takeda, Yoshio
    JOURNAL OF NATURAL MEDICINES, 2011, 65 (02) : 360 - 363
  • [7] Flavonol glycosides from the leaves of Indigofera zollingeriana
    Aya Hisaeda
    Katsuyoshi Matsunami
    Hideaki Otsuka
    Yoshio Takeda
    Journal of Natural Medicines, 2011, 65 : 360 - 363
  • [8] Natural Glycosides from Indigofera stachyoides radix
    Zhou, Wei
    Lei, Zhong
    Lai, Donna
    Li, George Q.
    Liang, Yan
    Zhang, Xiaoyan
    Cho, Junlae
    Hao, Xiaoyan
    RECORDS OF NATURAL PRODUCTS, 2020, 14 (01) : 83 - 88
  • [9] A lipase inhibitor monoterpene and monoterpene glycosides from Monarda punctata
    Yamada, Keiko
    Murata, Toshihiro
    Kobayashi, Kyoko
    Miyase, Toshio
    Yoshizaki, Fumihiko
    PHYTOCHEMISTRY, 2010, 71 (16) : 1884 - 1891
  • [10] Monoterpene glycosides from Paeonia veitchii
    Fu, Qiang
    Tan, Mao-Ling
    Yuan, Hai-Mei
    Chen, Jiang
    Fu, Jia
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 19 (01) : 22 - 27