Antimicrobial Peptide Preferential Binding of E. coli O157:H7

被引：17
|
作者：
Soares, Jason W. [1 ]
Kirby, Romy [1 ]
Morin, Kimberly M. [1 ]
Mello, Charlene M. [1 ]
机构：
[1] USA, Natick Soldier Res Dev & Engn Ctr, Biosci & Technol Team, Natick, MA 01760 USA
来源：
PROTEIN AND PEPTIDE LETTERS | 2008年 / 15卷 / 10期
关键词：
Antimicrobial peptide; E. coli O157:H7; preferential binding; molecular recognition; whole cell binding; surface plasmon resonance;
D O I：
10.2174/092986608786071049
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The studies presented here explore antimicrobial peptide preferential binding behavior for a target pathogen, Escherichia coli O157:H7. A modified immunoassay and surface plasmon resonance were employed to evaluate immobilized peptide binding of whole bacterial cells. The knowledge gained may guide the rational design of peptides with enhanced species binding selectivity.
引用
收藏
页码：1086 / 1093
页数：8
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