Exploration of differences between mechanism-based PK/PD and systems pharmacology models

被引：0
|
作者：
Demin, Oleg [1 ]
机构：
[1] Inst Syst Biol Moscow, Moscow, Russia
来源：
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS | 2016年 / 43卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
T-55
引用
收藏
页码：S73 / S73
页数：1
相关论文
共 50 条
  • [1] Mechanism-based organization of neural networks to emulate systems biology and pharmacology models
    Mann, John
    Meshkin, Hamed
    Zirkle, Joel
    Han, Xiaomei
    Thrasher, Bradlee
    Chaturbedi, Anik
    Arabidarrehdor, Ghazal
    Li, Zhihua
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [2] Deriving mechanism-based pharmacodynamic models by reducing quantitative systems pharmacology models: An application to warfarin
    Falkenhagen, Undine
    Knoechel, Jane
    Kloft, Charlotte
    Huisinga, Wilhelm
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2023, 12 (04): : 432 - 443
  • [3] The Pharmacokinetics/Pharmacodynamics of Resveratrol and Mechanism-based PK-PD Modeling Research
    Chen, Hui
    Liu, Xinxia
    Wan, Heng
    Zeng, Can
    FASEB JOURNAL, 2014, 28 (01):
  • [4] Mechanism-based PK/PD model for the lymphocytopenia induced by endogenous and exogenous corticosteroids
    Meibohm, B
    Derendorf, H
    Möllmann, H
    Fröhlich, P
    Tromm, A
    Wagner, M
    Homrighausen, S
    Krieg, M
    Hochhaus, G
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 1999, 37 (08) : 367 - 376
  • [5] Mechanism-based PK-PD modeling for prediction of efficacy-safety
    Danhof, M.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2007, 59 : A66 - A66
  • [6] MECHANISM-BASED PK-PD MODELING FOR PREDICTION OF EFFICACY-SAFETY
    Danhof, Meindert
    DRUG METABOLISM REVIEWS, 2007, 39 : 33 - 33
  • [7] Simulation from ODE-Based Population PK/PD and Systems Pharmacology Models in R with mrgsolve
    Baron, Kyle T.
    Gastonguay, Marc R.
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2015, 42 : S84 - S85
  • [8] Mechanism-based PK-PD model for Brain Dopamine Responses by Methylphenidate in Rats
    Shimizu, Ryosuke
    Horiguchi, Naotaka
    Yano, Koji
    Sakuramoto, Masashi
    Kanegawa, Naoki
    Shinohara, Shunji
    Ohnishi, Shuichi
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2017, 44 : S106 - S106
  • [9] Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research
    Danhof, Meindert
    de Lange, Elizabeth C. M.
    Della Pasqua, Oscar E.
    Ploeger, Bart A.
    Voskuyl, Rob A.
    TRENDS IN PHARMACOLOGICAL SCIENCES, 2008, 29 (04) : 186 - 191
  • [10] A Mechanism-Based PK/PD Model for Hematological Toxicities Induced by Antibody-Drug Conjugates
    Ait-Oudhia, Sihem
    Zhang, Weiyan
    Mager, Donald E.
    AAPS JOURNAL, 2017, 19 (05): : 1436 - 1448
12345