Enzymatic synthesis of 4-O-beta-D-galactopyranosyl-moranoline and 3-O-beta-D-galactopyranosyl-moranoline by using beta-galactosidase from Bacillus circulans

被引：7
|
作者：
Kojima, M
Seto, T
Kyotani, Y
Ogawa, H
Kitazawa, S
Mori, K
Maruo, S
Ohgi, T
Ezure, Y
机构：
[1] Discovery Research Lab III, Nippon Shinyaku Co Ltd, Kyoto, 601, Nishioji-hachijo, Minami-ku
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1996年 / 60卷 / 04期
关键词：
moranoline; 1-deoxynojirimycin; 3-O-beta-D-galactopyranosyl-moranoline; 4-O-beta-D-galactopyranosyl-moranoline; galactosidase;
D O I：
10.1271/bbb.60.694
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A transgalactosylation reaction from lactose to moranoline (1-deoxynojirimycin) was accomplished by using beta-galactosidase [EC 3.2.1.23] from Bacillus circulans. The enzyme formed 3-O-beta-D-galactopyranosyl-moranoline and 4-O-beta-D-galactopyransoyl-moranoline as major products, together with 2-O-beta-D-galactopyranosyl-moranoline and 6-O-beta-D-galactopyranosyl-moranoline as minor ones.
引用
收藏
页码：694 / 696
页数：3
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