Two New Highly Oxygenated and Rearranged Limonoids from Phyllanthus cochinchinensis

被引：22
|
作者：
Zhao, Jian-Qiang [1 ,2 ]
Wang, Yan-Ming [1 ,2 ]
He, Hong-Ping [1 ]
Li, Sheng-Hong [1 ]
Li, Xiao-Nian [1 ]
Yang, Chong-Ren [1 ]
Wang, Dong [1 ]
Zhu, Hong-Tao [1 ]
Xu, Min [1 ]
Zhang, Ying-Jun [1 ]
机构：
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 10期
基金：
中国科学院西部之光基金;
关键词：
APHANAMIXIS-POLYSTACHYA; WALSURA-COCHINCHINENSIS; BLOCKERS; SKELETON; EMBLICA; POTENT; ROOTS;
D O I：
10.1021/ol400875n
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new 6/6/5/6-fused limonoid, phyllanthoid A (1), possessing both 19/30 and 19/29 oxygen bridges was isolated from Phyllanthus cochinchinensis (Euphorbiaceae), together with a new related limonoid, phyllanthoid B (2). Their structures were determined by spectroscopic analysis and single-crystal X-ray diffraction in the case of 1. Compound 1 displayed moderate antifeedant against the generalist plant-feeding insect Spodoptera exigua and cytotoxicity against the MCF-7 cell line.
引用
收藏
页码：2414 / 2417
页数：4
相关论文
共 50 条
  • [1] New rearranged limonoids from Walsura cochinchinensis
    Han, Mei-Ling
    Shen, Yu
    Leng, Ying
    Zhang, Hua
    Yue, Jian-Min
    RSC ADVANCES, 2014, 4 (37): : 19150 - 19158
  • [2] Highly Oxygenated Limonoids and Lignans from Phyllanthus flexuosus
    Zhao J.-Q.
    Wang Y.-M.
    Zhu H.-T.
    Wang D.
    Li S.-H.
    Cheng R.-R.
    Yang C.-R.
    Wang Y.-F.
    Xu M.
    Zhang Y.-J.
    Natural Products and Bioprospecting, 2014, 4 (4) : 233 - 242
  • [3] Walsucochinoids A and B: New Rearranged Limonoids from Walsura cochinchinensis
    Han, Mei-Ling
    Zhang, Hua
    Yang, Sheng-Ping
    Yue, Jian-Min
    ORGANIC LETTERS, 2012, 14 (02) : 486 - 489
  • [4] Highly oxygenated and rearranged limonoids from the stem barks of Entandrophragma utile
    Hu, Ya-Lin
    Tian, Xiao-Meng
    Wang, Cheng-Cheng
    Olga, Quasie
    Yan, Dan
    Tang, Peng-Fei
    Zhang, Li-Na
    Luo, Jun
    Kong, Ling-Yi
    PHYTOCHEMISTRY, 2020, 172
  • [5] New Phenolic Glycosides from Phyllanthus cochinchinensis
    Zhao, Jian-Qiang
    Wang, Yan-Ming
    Lv, Jun-Jiang
    Zhu, Hong-Tao
    Wang, Dong
    Yang, Chong-Ren
    Xu, Min
    Zhang, Ying-Jun
    JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2014, 25 (08) : 1446 - 1454
  • [6] Three new highly oxygenated diterpenoids from Excoecaria cochinchinensis LOUR.
    Yang, JH
    Luo, SD
    Zhao, JF
    Wang, YS
    Huang, R
    Zhang, HB
    Li, L
    HELVETICA CHIMICA ACTA, 2005, 88 (05) : 968 - 973
  • [7] New rearranged limonoids from Harrisonia perforata
    Khuong-Huu, Q
    Chiaroni, A
    Riche, C
    Nguyen-Ngoc, H
    Nguyen-Viet, K
    Khuong-Huu, F
    JOURNAL OF NATURAL PRODUCTS, 2000, 63 (07): : 1015 - 1018
  • [8] Phainanolide A, Highly Modified and Oxygenated Triterpenoid from Phyllanthus hainanensis
    Fan, Yao-Yue
    Gan, Li-She
    Liu, Hong-Chun
    Li, Heng
    Xu, Cheng-Hui
    Zuo, Jian-Ping
    Ding, Jian
    Yue, Jian-Min
    ORGANIC LETTERS, 2017, 19 (17) : 4580 - 4583
  • [9] Cytotoxic limonoids from the bark of Walsura cochinchinensis
    Trinh, Binh T. D.
    Nguyen, Hiep D.
    Nguyen, Hieu T.
    Pham, Phuoc D.
    Ngo, Ngoc T. N.
    Nguyen, Le-Thu T.
    Nguyen, Ly T. T.
    Bui, Dzung N.
    Dang, Son, V
    Nguyen, Lien-Hoa D.
    FITOTERAPIA, 2019, 133 : 75 - 79
  • [10] Five new sucrose esters from the whole plants of Phyllanthus cochinchinensis
    Zhao J.-Q.
    Wang Y.-M.
    Wang D.
    Yang C.-R.
    Xu M.
    Zhang Y.-J.
    Natural Products and Bioprospecting, 2013, 3 (2) : 61 - 65
12345