High-intensity focused ultrasound: advances in technology and experimental trials support enhanced utility of focused ultrasound surgery in oncology

被引:53
|
作者
Malietzis, G. [1 ]
Monzon, L. [1 ]
Hand, J. [2 ]
Wasan, H. [1 ,3 ]
Leen, E. [4 ]
Abel, M. [1 ]
Muhammad, A. [1 ]
Price, P. [1 ]
Abel, P. [1 ,5 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Surg & Canc, Fac Med, London, England
[2] Kings Coll London, Imaging Sci & Biomed Engn Div, London WC2R 2LS, England
[3] Imperial Coll NHS Trust, Hammersmith Hosp, Dept Oncol, London, England
[4] Univ London Imperial Coll Sci Technol & Med, Dept Med, London, England
[5] Imperial Coll NHS Trust, Dept Urol, Charing Cross Hosp, London, England
来源
BRITISH JOURNAL OF RADIOLOGY | 2013年 / 86卷 / 1024期
关键词
RECURRENT PROSTATE-CANCER; PHASED-ARRAY; RENAL TUMORS; HEPATOCELLULAR-CARCINOMA; PANCREATIC-CANCER; SALVAGE THERAPY; ABLATION; BREAST; HYPERTHERMIA; TRANSDUCERS;
D O I
10.1259/bjr.20130044
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
High-intensity focused ultrasound (HIFU) is a rapidly maturing technology with diverse clinical applications. In the field of oncology, the use of HIFU to non-invasively cause tissue necrosis in a defined target, a technique known as focused ultrasound surgery (FUS), has considerable potential for tumour ablation. In this article, we outline the development and underlying principles of HIFU, overview the limitations and commercially available equipment for FUS, then summarise some of the recent technological advances and experimental clinical trials that we predict will have a positive impact on extending the role of FUS in cancer therapy.
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页数:12
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