Mesenchymal stromal cells support significant engraftment of low-risk myelodysplastic syndromes (MDS) in a murine xenograft model

被引:0
|
作者
Medyouf, H. [1 ]
Mossner, M. [2 ]
Nolte, F. [2 ]
Jann, J. C. [2 ]
Nowak, V. [2 ]
Zens, B. [1 ]
Muedder, K. [1 ]
Oblaender, J. [2 ]
Fey, S. [2 ]
Fabarius, A. [2 ]
Riedl, E. [3 ]
Marx, A. [3 ]
Roehl, H. [4 ]
Mueller, N. [2 ]
Metzgeroth, G. [2 ]
Huetter, G. [5 ]
Hofmann, W. K. [2 ]
Trumpp, A. [6 ]
Nowak, D. [2 ]
机构
[1] German Canc Res Ctr, Dept Stem Cells & Canc, Heidelberg, Germany
[2] Heidelberg Univ, Med Fac Mannheim, Dept Hematol & Oncol, Mannheim, Germany
[3] Heidelberg Univ, Med Fac Mannheim, Dept Pathol, Mannheim, Germany
[4] Heidelberg Univ, Med Fac Mannheim, Dept Orthoped, Mannheim, Germany
[5] Heidelberg Univ, Med Fac Mannheim, Dept Transfus Med, Mannheim, Germany
[6] German Canc Res Ctr, Dept Stem Cells & Canc HiStem GmbH, Heidelberg, Germany
关键词
D O I
10.1016/S0145-2126(13)70035-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
O-013
引用
收藏
页码:S14 / S14
页数:1
相关论文
共 49 条
  • [1] Significant Engraftment of Immature Hematopoietic Cells From Patients with Low Risk Myelodysplastic Syndromes (MDS) in Immunodeficient Mice
    Medyouf, Hind
    Nolte, Florian
    Mossner, Maximilian
    Nowak, Verena
    Zens, Bettina
    Muedder, Katja
    Oblaender, Julia
    Fey, Stephanie
    Klaumuenzer, Marion
    Fabarius, Alice
    Riedl, Eva
    Marx, Alexander
    Roehl, Henning
    Mueller, Nadine
    Metzgeroth, Georgia
    Huetter, Gero
    Hofmann, Wolf-Karsten
    Trumpp, Andreas
    Nowak, Daniel
    BLOOD, 2012, 120 (21)
  • [2] An accessible patient-derived xenograft model of low-risk myelodysplastic syndromes
    Teodorescu, Patric
    Pasca, Sergiu
    Choi, Inyoung
    Shams, Cynthia
    Dalton, W. Brian
    Gondek, Lukasz P.
    DeZern, Amy E.
    Ghiaur, Gabriel
    HAEMATOLOGICA, 2024, 109 (01) : 337 - 342
  • [3] Response assessments in low-risk and high-risk myelodysplastic syndromes (MDS)
    Fenaux, P
    SEMINARS IN ONCOLOGY, 2005, 32 (04) : S11 - S15
  • [4] Eltrombopag restores proliferative capacity and adipose-osteogenic balance of mesenchymal stromal cells in low-risk myelodysplastic syndromes
    Hong, Minghua
    Guo, Juan
    Zhao, Youshan
    Song, Luxi
    Zhao, Sida
    Wang, Roujia
    Shi, Lei
    Zhang, Zheng
    Wu, Dong
    He, Qi
    Chang, Chunkang
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2024, 985
  • [5] HEPCIDIN AND ERYTHROFERRONE (ERFE) ARE NOT CORRELATED IN THE ANEMIA OF LOW-RISK MYELODYSPLASTIC SYNDROMES (MDS)
    Redondo, S.
    Oarbeascoa, G.
    Moran Jimenez, M. J.
    Domingo, A.
    Munoz Linares, C.
    Moreno Carralero, M. I.
    Bellon, J. M.
    Del Campo Rincon, J. F.
    Diez-Martin, J. L.
    Font, P.
    HAEMATOLOGICA, 2018, 103 : 183 - 184
  • [6] MESENCHYMAL STROMAL CELLS MAY ENHANCE RESIDUAL HEALTHY HAEMATOPOIESIS IN LOW-RISK MDS PATIENTS
    Jimenez Solas, T.
    Muntion Olave, S.
    Lopez, F.
    Ortega Herrera, R.
    Martin Izquierdo, M.
    Gonzalez Martinez, T.
    Janusz, K.
    Ezponda, T.
    Vilas, A.
    Alfonso, A.
    Prosper, F.
    Molero, A.
    Valcarcel, D.
    Sanchez-Guijo, F.
    Diez-Campelo, M.
    LEUKEMIA RESEARCH, 2021, 108 : S39 - S39
  • [7] IN VITRO STUDY OF BIOLOGICAL CHARACTERISTICS AND FUNCTIONS OF MESENCHYMAL STEM CELLS IN LOW-RISK MYELODYSPLASTIC SYNDROMES
    Zhang, Y. Z.
    Zhao, D. D.
    Han, X. P.
    Da, W. M.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 : 376 - 377
  • [8] Mesenchymal stromal cells promote tumor engraftment and progression in tumor xenograft model
    Park, Gyeongsin
    Song, Byunghoo
    Lee, Seonghak
    Jung, Chan Kwon Jung
    Lee, Ahwon
    Chung, Yang-Guk
    Choi, Yeong-Jin
    Lee, Kyo-Young
    Kang, Chang Suk
    CANCER RESEARCH, 2013, 73 (08)
  • [9] Pathogenesis of iron overload in myelodysplastic syndromes and the debate on iron chelation in low-risk MDS
    Shenoy, Niraj
    Verma, Amit
    Ginzburg, Yelena
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2014, 34 : S85 - S85
  • [10] The Different Immunoregulatory Functions of Mesenchymal Stem Cells in Patients with Low-Risk or High-Risk Myelodysplastic Syndromes
    Zhao, Zhigang
    Wang, Zhenling
    Li, Qiubai
    Li, Weiming
    You, Yong
    Zou, Ping
    PLOS ONE, 2012, 7 (09):