Breast cancer in Finistere, France: Epidemiological description and tendencies over a 10-year period (2000-2009) according to pathology data

The aim of this study was the description of breast carcinoma over a 10-year period according to pathology data. Method. - Descriptive epidemiological study based on data collection of pathological code ADI-CAP (injury, organ, and applied technical), histological, hormonal, node and administrative data. From January 1st 2000 to December 31st 2009, 6186 Women living in Finistere have had a diagnosis of invasive breast carcinoma. The incidence rate involved from 125 per 100,000 women to 136 in 2009. Average age to the first diagnosis was 61.4 +/- 13.6; class of age with the more important incidence rate was for the 50-74 years old. The different histological subtypes varied over the period (P < 0.0001). Tumour's size was notified for more than 75% in the whole period of the study. The average size evolved significantly over the period (P < 0.0001 from 23.5 mm [+/-18.4] in 2000 to 21.02 [+/-16.2] in 2009, particularly after 2003 [P < 0.0002]). The grade status (SBR, MSBR and Elston Ellis) showed a trend to the gravity decrease over the period (respectively P = 0.03 [r(2) = -0,04]; P < 0.0001 [r(2) = -0.10]; P < 0.0001 [r(2) = -0.08]). Conclusion. - Our results confirm the interest of pathology database for the description of invasive breast cancer. (C) 2012 Elsevier Masson SAS. All rights reserved.