INstruct: a database of high-quality 3D structurally resolved protein interactome networks

被引：105

作者：

Meyer, Michael J. ^{[1
,2
,3
]}

Das, Jishnu ^{[1
,2
]}

Wang, Xiujuan ^{[1
,2
]}

Yu, Haiyuan ^{[1
,2
]}

机构：

[1] Cornell Univ, Dept Biol Stat & Computat Biol, Ithaca, NY 14853 USA

[2] Cornell Univ, Weill Inst Cell & Mol Biol, Ithaca, NY 14853 USA

[3] Tri Inst Training Program Computat Biol & Med, New York, NY 10065 USA

来源：

BIOINFORMATICS | 2013年 / 29卷 / 12期

关键词：

MOLECULAR INTERACTION DATABASE;

D O I：

10.1093/bioinformatics/btt181

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

INstruct is a database of high-quality, 3D, structurally resolved protein interactome networks in human and six model organisms. INstruct combines the scale of available high-quality binary protein interaction data with the specificity of atomic-resolution structural information derived from co-crystal evidence using a tested interaction interface inference method. Its web interface is designed to allow for flexible search based on standard and organism-specific protein and gene-naming conventions, visualization of protein architecture highlighting interaction interfaces and viewing and downloading custom 3D structurally resolved interactome datasets.

引用

页码：1577 / 1579

页数：3

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