Nasopharyngeal Nonkeratinizing (Undifferentiated) Monstrous Cell Carcinoma A Case Report

被引:0
|
作者
Avci, Arzu [2 ]
Gunhan, Omer [1 ]
Karslioglu, Yildirim [1 ]
Celasun, Bulent [3 ]
机构
[1] Gulhane Mil Med Acad, Dept Pathol, TR-06018 Ankara, Turkey
[2] Ataturk Res & Educ Hosp, Izmir, Turkey
[3] Goren Pathol Lab, Ankara, Turkey
来源
关键词
Epstein-Barr virus; monstrous cell; nasopharyngeal carcinoma; nonkeratinizing carcinoma; tumor giant cell; FLOW-CYTOMETRIC ANALYSIS;
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
BACKGROUND: The histologic type of nasopharyngeal carcinoma can be an important factor in the prognosis. The effects, if any, of the degree of cellular pleomorphism is uncertain. CASE: In this report, we present a case of nonkeratinizing, undifferentiated nasopharyngeal carcinoma with monstrous tumor giant cells. An extremely high level of aneuploidy and dense cytoplasmic accumulation of Epstein-Barr virus capsid antigen were found in tumor cells. The patient was treated with concomitant chemoradiotherapy. CONCLUSION: Nine years of follow-up with no recurrences suggests that this extreme morphologic variation may impart no adverse prognostic effect. (Anal Quant Cytol Histol 2011;33:297-302)
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页码:297 / 302
页数:6
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