A new linear solvation energy relationship for the solubility of liquids in water

被引：13
|
作者：
Lee, SB
机构：
[1] Department of Chemical Engineering, Pohang Univ. of Sci. and Technology, Pohang 790-784, San 31, Hyoja Dong
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 1996年 / 85卷 / 03期
关键词：
D O I：
10.1021/js950228y
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
From a comparison between the linear solvation energy relationship (LSER) and the extended solubility parameter model, it has been found that the solute-solute interaction energy term is missing in the LSER equation. A new LSER equation with the supplementary interaction energy ten has been proposed for the solvation process. It is shown that the new LSER equation yields the correct solute-solvent interaction terms for the solubilities of liquids in water.
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页码：348 / 350
页数：3
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