Synergistic effect of olaparib (AZD2281) with combination of cisplatin on PTEN-deficient lung cancer cell lines

被引：0
|
作者：
Minami, Daisuke [1 ]
Takigawa, Nagio [2 ]
Takeda, Hiromasa [3 ]
Takata, Minoru [4 ]
Ichihara, Eiki [1 ]
Hisamoto, Akiko [1 ]
Hotta, Katsyuyuki [1 ]
Tabata, Masahiro [1 ]
Tanimoto, Mitsune [1 ]
Kiura, Katsuyuki [1 ]
机构：
[1] Okayama Univ Hosp, Okayama, Japan
[2] Kawasaki Med Sch, Okayama, Japan
[3] Tottori Municipal Hosp, Tottori, Japan
[4] Kyoto Univ, Kyoto, Japan
来源：
CANCER RESEARCH | 2012年 / 72卷
关键词：
D O I：
10.1158/1538-7445.AM2012-4686
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
4686
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Synergistic Effect of Olaparib with Combination of Cisplatin on PTEN-Deficient Lung Cancer Cells
    Minami, Daisuke
    Takigawa, Nagio
    Takeda, Hiromasa
    Takata, Minoru
    Ochi, Nobuaki
    Ichihara, Eiki
    Hisamoto, Akiko
    Hotta, Katsuyuki
    Tanimoto, Mitsune
    Kiura, Katsuyuki
    MOLECULAR CANCER RESEARCH, 2013, 11 (02) : 140 - 148
  • [2] Combination of AZD2281 (Olaparib) and GX15-070 (Obatoclax) results in synergistic antitumor activities in preclinical models of pancreatic cancer
    Chen, Shaohua
    Wang, Guan
    Niu, Xiaojia
    Zhao, Jianyun
    Tan, Wenxi
    Wang, Hebin
    Zhao, Lijing
    Ge, Yubin
    CANCER LETTERS, 2014, 348 (1-2) : 20 - 28
  • [3] Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin
    Evers, Bastiaan
    Drost, Rinske
    Schut, Eva
    de Bruin, Michiel
    van der Burg, Eline
    Derksen, Patrick W. B.
    Holstege, Henne
    Liu, Xiaoling
    van Drunen, Ellen
    Beverloo, H. Berna
    Smith, Graeme C. M.
    Martin, Niall M. B.
    Lau, Alan
    O'Connor, Mark J.
    Jonkers, Jos
    CLINICAL CANCER RESEARCH, 2008, 14 (12) : 3916 - 3925
  • [4] A phase I combination study of olaparib (AZD2281; KU-0059436) and cisplatin plus gemcitabine in adults with solid tumors
    Rajan, Arun
    Carter, Corey A.
    Gutierrez, Martin
    Kummar, Shivaani
    Yancey, Mary Ann
    Ji Jiuping
    Zhang Yiping
    Simmons, Dwight
    Parchment, Ralph
    Tomaszewski, Joseph
    Doroshow, James H.
    Giaccone, Giuseppe
    JOURNAL OF THORACIC ONCOLOGY, 2009, 4 (09) : S598 - S599
  • [5] Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer
    Audeh, M. W.
    Penson, R. T.
    Friedlander, M.
    Powell, B.
    Bell-McGuinn, K. M.
    Scott, C.
    Weitzel, J. N.
    Carmichael, J.
    Tutt, A.
    JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
  • [6] PHASE I COMBINATION STUDY OF OLAPARIB (AZD2281; KU-0059436) AND CISPLATIN (C) PLUS GEMCITABINE (G) IN ADULTS WITH SOLID TUMORS
    Rajan, A.
    Kelly, R. J.
    Gutierrez, M.
    Kummar, S.
    Yancey, M. A.
    Ji, J.
    Zhang, Y.
    Parchment, R.
    Doroshow, J.
    Giaccone, G.
    ANNALS OF ONCOLOGY, 2010, 21 : 17 - 17
  • [7] Pre-clinical activity of the PARP inhibitor AZD2281 in human breast cancer cell lines and in combination with DNA damaging agents
    Finn, R. S.
    Lau, A.
    Kalous, O.
    Conklin, D.
    Dering, J.
    Knights, C.
    O'Shaughnessy, A.
    Cranston, A.
    Riches, L.
    Carmichael, J.
    O'Connor, M. J.
    Slamon, D. J.
    CANCER RESEARCH, 2009, 69 (02) : 117S - 117S
  • [8] A phase I combination study of olaparib (AZD2281; KU-0059436) and cisplatin (C) plus gemcitabine (G) in adults with solid tumors.
    Giaccone, G.
    Rajan, A.
    Kelly, R. J.
    Gutierrez, M.
    Kummar, S.
    Yancey, M.
    Ji, J. J.
    Zhang, Y.
    Parchment, R. E.
    Doroshow, J. H.
    JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (15)
  • [9] STOMP: Small cell lung cancer trial of olaparib (AZD2281) as maintenance programme - a randomised, double blind, multicentre NCRN phase II trial
    Woll, P. J.
    Jarrett, H.
    Billingham, L.
    LUNG CANCER, 2011, 71 : S42 - S42
  • [10] APR-246 (PRIMA-1MET) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines
    Deben, Christophe
    Lardon, Filip
    Wouters, An
    Op de Beeck, Ken
    Van den Bossche, Jolien
    Jacobs, Julie
    Van der Steen, Nele
    Peeters, Marc
    Rolfo, Christian
    Deschoolmeester, Vanessa
    Pauwels, Patrick
    CANCER LETTERS, 2016, 375 (02) : 313 - 322
12345