Replacement of Red and Processed Meat With Other Food Sources of Protein and the Risk of Type 2 Diabetes in European Populations: The EPIC-InterAct Study

被引：39

作者：

Ibsen, Daniel B. ^{[1
,2
]}

Steur, Marinka ^{[2
]}

Imamura, Fumiaki ^{[2
]}

Overvad, Kim ^{[1
,3
]}

Schulze, Matthias B. ^{[4
,5
,6
]}

Bendinelli, Benedetta ^{[7
]}

Guevara, Marcela ^{[8
,9
,10
]}

Agudo, Antonio ^{[11
,12
]}

Amiano, Pilar ^{[9
,13
,14
]}

Aune, Dagfinn ^{[15
,16
,17
]}

Barricarte, Aurelio ^{[8
]}

Ericson, Ulrika ^{[18
]}

Fagherazzi, Guy ^{[19
,20
]}

Franks, Paul W. ^{[21
]}

Freisling, Heinz ^{[22
]}

Quiros, Jose R. ^{[23
]}

Grioni, Sara ^{[24
]}

Heath, Alicia K. ^{[15
]}

Huybrechts, Inge ^{[22
]}

Katze, Verena ^{[25
]}

Laouali, Nasser ^{[20
]}

Mancini, Francesca ^{[20
]}

Masala, Giovanna ^{[7
]}

Olsen, Anja ^{[1
,26
]}

Papier, Keren ^{[27
]}

Ramne, Stina ^{[18
]}

Rolandsson, Olov ^{[28
]}

Sacerdote, Carlotta ^{[29
,30
]}

Sanchez, Maria-Jose ^{[9
,31
,32
,33
]}

Santiuste, Carmen ^{[9
,34
]}

Simeon, Vittorio ^{[35
]}

Spijkerman, Annemieke M. W. ^{[36
]}

Srour, Bernard ^{[25
]}

Tjonneland, Anne ^{[26
,37
]}

Tong, Tammy Y. N. ^{[27
]}

Tumino, Rosario ^{[38
,39
]}

van der Schouw, Yvonne T. ^{[40
]}

Weiderpass, Elisabete ^{[22
]}

Wittenbecher, Clemens ^{[4
,5
,41
]}

Sharp, Stephen J. ^{[2
]}

Riboli, Elio ^{[15
]}

Forouhi, Nita G. ^{[2
]}

Wareham, Nick J. ^{[2
]}

机构：

[1] Aarhus Univ, Dept Publ Hlth, Res Unit Epidemiol, Aarhus, Denmark

[2] Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge, England

[3] Aalborg Univ Hosp, Dept Cardiol, Aalborg, Denmark

[4] German Inst Human Nutr Potsdam Rehbrucke, Dept Mol Epidemiol, Nuthetal, Germany

[5] German Ctr Diabet Res DZD, Neuherberg, Germany

[6] Univ Potsdam, Inst Nutr Sci, Nuthetal, Germany

[7] Inst Canc Res Prevent & Clin Network ISPRO, Canc Risk Factors & Lifestyle Epidemiol Unit, Florence, Italy

[8] Navarre Publ Hlth Inst, Pamplona, Spain

[9] CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain

[10] Navarra Inst Hlth Res IdiSNA, Pamplona, Spain

[11] Bellvitge Biomed Res Inst IDIBELL, Catalan Inst Oncol ICO, Unit Nutr & Canc, Barcelona, Spain

[12] Bellvitge Biomed Res Inst IDIBELL, Nutr & Canc Grp, Barcelona, Spain

[13] Publ Hlth Div Gipuzkoa, San Sebastian, Spain

[14] Inst Biodonostia, Basque Govt, San Sebastian, Spain

[15] Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England

[16] Bjorknes Univ Coll, Dept Nutr, Oslo, Norway

[17] Oslo Univ Hosp Ulleval, Dept Endocrinol Morbid Obes & Prevent Med, Oslo, Norway

[18] Lund Univ, Dept Clin Sci, Malmo, Sweden

[19] Luxembourg Inst Hlth, Dept Populat Hlth, Digital Epidemiol & eHlth Res Hub, Luxembourg, Luxembourg

[20] Paris South Paris Saclay Univ, INSERM, Ctr Epidemiol & Populat Hlth, Inst Gustave Roussy,UMR 1018, Villejuif, France

[21] Lund Univ, Malmo, Sweden

[22] WHO, Int Agcy Res Canc, Lyon, France

[23] Publ Hlth Directorate, Asturias, Spain

[24] Fdn IRCCS Ist Nazl Tumori, Epidemiol & Prevent Unit, Milan, Italy

[25] German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany

[26] Danish Canc Soc Res Ctr, Copenhagen, Denmark

[27] Univ Oxford, Nuffield Dept Populat Hlth, Canc Epidemiol Unit, Oxford, England

[28] Umea Univ, Dept Publ Hlth & Clin Med, Family Med, Umea, Sweden

[29] Azienda Osped Univ Citta Salute & Sci Torino, Unit Canc Epidemiol, Turin, Italy

[30] Ctr Canc Prevent CPO, Turin, Italy

[31] Escuela Andaluza & Salud Publ, Granada, Spain

[32] Inst Invest Biosanitaria Ibs Granda, Granada, Spain

[33] Univ Granada, Dept Prevent Med & Publ Hlth, Granada, Spain

[34] IMIB Arrixaca, Dept Epidemiol, Murcia Reg Hlth Author, Murcia, Spain

[35] Univ Campania Luigi Vanvitelli, Dept Mental & Phys Hlth & Prevent Med, Naples, Italy

[36] Natl Inst Publ Hlth & Environm RIVM, Bilthoven, Netherlands

[37] Univ Copenhagen, Dept Publ Hlth, Copenhagen, Denmark

[38] Azienda Sanitaria Prov, Canc Registry & Histopathol Dept, Ragusa, Italy

[39] Org Non Lucrativa Utilit a Sociale AIRE ONLUS, Assoc Ibleaper Ric Epidemiol, Ragusa, Italy

[40] Univ Utrecht, Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands

[41] Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA

来源：

DIABETES CARE | 2020年 / 43卷 / 11期

关键词：

CONSUMPTION; ASSOCIATION; CANCER; MELLITUS; IRON; METAANALYSIS; COUNTRIES; FERRITIN; VALIDITY; MEN;

D O I：

10.2337/dc20-1038

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE There is sparse evidence for the association of suitable food substitutions for red and processed meat on the risk of type 2 diabetes. We modeled the association between replacing red and processed meat with other protein sources and the risk of type 2 diabetes and estimated its population impact. RESEARCH DESIGN AND METHODS The European Prospective Investigation into Cancer (EPIC)-InterAct case cohort included 11,741 individuals with type 2 diabetes and a subcohort of 15,450 participants in eight countries. We modeled the replacement of self-reported red and processed meat with poultry, fish, eggs, legumes, cheese, cereals, yogurt, milk, and nuts. Country-specific hazard ratios (HRs) for incident type 2 diabetes were estimated by Prentice-weighted Cox regression and pooled using random-effects meta-analysis. RESULTS There was a lower hazard for type 2 diabetes for the modeled replacement of red and processed meat (50 g/day) with cheese (HR 0.90, 95% CI 0.83-0.97) (30 g/day), yogurt (0.90, 0.86-0.95) (70 g/day), nuts (0.90, 0.84-0.96) (10 g/day), or cereals (0.92, 0.88-0.96) (30 g/day) but not for replacements with poultry, fish, eggs, legumes, or milk. If a causal association is assumed, replacing red and processed meat with cheese, yogurt, or nuts could prevent 8.8%, 8.3%, or 7.5%, respectively, of new cases of type 2 diabetes. CONCLUSIONS Replacement of red and processed meat with cheese, yogurt, nuts, or cereals was associated with a lower rate of type 2 diabetes. Substituting red and processed meat by other protein sources may contribute to the prevention of incident type 2 diabetes in European populations.

引用

页码：2660 / 2667

页数：8

共 50 条

[1] Smoking and Long-Term Risk of Type 2 Diabetes: The EPIC-InterAct Study in European Populations
Spijkerman, Annemieke M. W.
van der A, Daphne L.
Nilsson, Peter M.
Ardanaz, Eva
Gavrila, Diana
Agudo, Antonio
Arriola, Larraitz
Balkau, Beverley
Beulens, Joline W.
Boeing, Heiner
de Lauzon-Guillain, Blandine
Fagherazzi, Guy
Feskens, Edith J. M.
Franks, Paul W.
Grioni, Sara
Huerta, Jose Maria
Kaaks, Rudolf
Key, Timothy J.
Overvad, Kim
Palli, Domenico
Panico, Salvatore
Redondo, M. Luisa
Rolandsson, Olov
Roswal, Nina
Sacerdote, Carlotta
Sanchez, Maria-Jose
Schulze, Matthias B.
Slimani, Nadia
Teucher, Birgit
Tjonneland, Anne
Tumino, Rosario
van der Schouw, Yvonne T.
Langenberg, Claudia
Sharp, Stephen J.
Forouhi, Nita G.
Riboli, Elio
Wareham, Nicholas J.
DIABETES CARE, 2014, 37 (12) : 3164 - 3171
[2] Smoking and risk of type 2 diabetes: the EPIC-InterAct study
Spijkerman, A. M. W.
van der A, D. L.
Nilsson, P. M.
Ardanaz, E.
Gavrila, D.
DIABETOLOGIA, 2013, 56 : S162 - S162
[3] Age at menarche and type 2 diabetes risk: the EPIC-InterAct study
Elks, C.
DIABETOLOGIA, 2013, 56 : S175 - S175
[4] Adherence to predefined dietary patterns and incident type 2 diabetes in European populations: EPIC-InterAct study
Kroeger, J.
DIABETOLOGIA, 2013, 56 : S162 - S162
[5] Adherence to predefined dietary patterns and incident type 2 diabetes in European populations: EPIC-InterAct Study
Kroeger, Janine
Schulze, Matthias B.
Romaguera, Dora
Guevara, Marcela
Buijsse, Brian
Boeing, Heiner
Beulens, Joline W. J.
Feskens, Edith J. M.
Amiano, Pilar
Ardanaz, Eva
Agnoli, Claudia
Buckland, Genevieve
Clavel-Chapelon, Francoise
Dahm, Christina C.
Fagherazzi, Guy
Franks, Paul W.
Kaaks, Rudolf
Key, Timothy J.
Khaw, Kay Tee
Lajous, Martin
Mattiello, Amalia
Menendez Garcia, Virginia
Navarro, Carmen
Nilsson, Peter M.
Overvad, Kim
Palli, Domenico
Ricceri, Fulvio
Rolandsson, Olov
Sanchez, Maria-Jose
Slimani, Nadia
Spijkerman, Annemieke M. W.
Tjonneland, Anne
Tumino, Rosario
van der A, Daphne L.
Langenberg, Claudia
Sharp, Stephen J.
Forouhi, Nita G.
Riboli, Elio
Wareham, Nicholas J.
DIABETOLOGIA, 2014, 57 (02) : 321 - 333
[6] The EPIC-InterAct Study: A Study of the Interplay between Genetic and Lifestyle Behavioral Factors on the Risk of Type 2 Diabetes in European Populations
Forouhi N.G.
Wareham N.J.
Current Nutrition Reports, 2014, 3 (4) : 355 - 363
[7] Age at Menarche and Type 2 Diabetes Risk The EPIC-InterAct study
Elks, Cathy E.
Ong, Ken K.
Scott, Robert A.
van der Schouw, Yvonne T.
Brand, Judith S.
Wark, Petra A.
Amiano, Pilar
Balkau, Beverley
Barricarte, Aurelio
Boeing, Heiner
Fonseca-Nunes, Ana
Franks, Paul W.
Grioni, Sara
Halkjaer, Jytte
Kaaks, Rudolf
Key, Timothy J.
Khaw, Kay Tee
Mattiello, Amalia
Nilsson, Peter M.
Overvad, Kim
Palli, Domenico
Quiros, J. Ramon
Rinaldi, Sabina
Rolandsson, Olov
Romieu, Isabelle
Sacerdote, Carlotta
Sanchez, Maria-Jose
Spijkerman, Annemieke M. W.
Tjonneland, Anne
Tormo, Maria-Jose
Tumino, Rosario
Daphne, L. Van der A.
Forouhi, Nita G.
Sharp, Stephen J.
Langenberg, Claudia
Riboli, Elio
Wareham, Nicholas J.
DIABETES CARE, 2013, 36 (11) : 3526 - 3534
[8] Adherence to predefined dietary patterns and incident type 2 diabetes in European populations: EPIC-InterAct Study
Diabetologia, 2014, 57 : 321 - 333
[9] The association between dietary flavonoid and lignan intakes and incident type 2 diabetes in European populations: the EPIC-InterAct study
Zamora-Ros, R.
DIABETOLOGIA, 2013, 56 : S160 - S160
[10] Association between dietary meat consumption and incident type 2 diabetes: the EPIC-InterAct study
Palli, D.
DIABETOLOGIA, 2013, 56 (01) : 47 - 59

← 1 2 3 4 5 →