Mechanism of Surface-Enhanced Raman Scattering and Its Application to Highly Sensitive Protein Detection

被引：1
|
作者：
Ozaki, Y. [1 ]
Itoh, T. [2 ]
Yoshida, K. [1 ,2 ]
Kitahama, Y. [1 ]
Han, X. X. [3 ]
Zhao, B. [3 ]
机构：
[1] Kwansei Gakuin Univ, Sch Sci & Technol, Sanda, Hyogo, Japan
[2] Natl Inst Adv Ind Sci & Technol, Hlth Technol Res Ctr, Takamatsu, Kagawa, Japan
[3] Jilin Univ, State Key Lab Supramol Struct & Mat, Changchun 130012, Peoples R China
来源：
SPECTROSCOPY AND SPECTRAL ANALYSIS | 2009年 / 29卷 / 02期
关键词：
PLASMON RESONANCE;
D O I：
10.3964/j.issn.1000-0593(2009)02-0396-03
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
Enormous SERS "hot spots" may emerge among metal aggregates formed on the edges between the two metal layers and also between the junctions of metal nanoparticles in the second metal layer. High-quality SERRS/SERS spectra with both high sensitivity and reproducibility were obtained, which are crucial for an analytical method. By using these metal sandwich substrates, SERS-based versatile protein detections have been effectively carried out. Ten times stronger SERRS spectra can be obtained from the Au/Ag sandwiches as compared to those from the Au/Au sandwiches, and the detection limits of the present method are much lower than those of conventional fluorescence and surface plasmon resonance based detection methods for the similar targets.
引用
收藏
页码：396 / 398
页数：3
相关论文
共 12 条
  • [1] Simplified protocol for detection of protein-ligand interactions via surface-enhanced resonance Raman scattering and surface-enhanced fluorescence
    Han, Xiao X.
    Kitahama, Yasutaka
    Tanaka, Yuhei
    Guo, Jie
    Xu, Wei Q.
    Zhao, Bing
    Ozaki, Yukihiro
    [J]. ANALYTICAL CHEMISTRY, 2008, 80 (17) : 6567 - 6572
  • [2] Fluorescein isothiocyanate linked immunoabsorbent assay based on surface-enhanced resonance Raman scattering
    Han, Xiao X.
    Cai, Lin J.
    Guo, Jie
    Wang, Chun X.
    Ruan, Wei D.
    Han, Wen Y.
    Xu, Wei Q.
    Zhao, Bing
    Ozaki, Yukihiro
    [J]. ANALYTICAL CHEMISTRY, 2008, 80 (08) : 3020 - 3024
  • [3] Analytical technique for label-free multi-protein detection-based on Western blot and surface-enhanced Raman scattering
    Han, Xiao X.
    Jia, Hui Y.
    Wang, Yan F.
    Lu, Zhi C.
    Wang, Chun X.
    Xu, Wei Q.
    Zhao, Bing
    Ozaki, Yukihiro
    [J]. ANALYTICAL CHEMISTRY, 2008, 80 (08) : 2799 - 2804
  • [4] Surface-enhanced resonance Raman scattering and background light emission coupled with plasmon of single Ag nanoaggregates
    Itoh, T
    Biju, V
    Ishikawa, M
    Kikkawa, Y
    Hashimoto, K
    Ikehata, A
    Ozaki, Y
    [J]. JOURNAL OF CHEMICAL PHYSICS, 2006, 124 (13):
  • [5] Direct demonstration for changes in surface plasmon resonance induced by surface-enhanced Raman scattering quenching of dye molecules adsorbed on single Ag nanoparticles
    Itoh, T
    Hashimoto, K
    Ikehata, A
    Ozaki, Y
    [J]. APPLIED PHYSICS LETTERS, 2003, 83 (26) : 5557 - 5559
  • [6] Polarization dependences of surface plasmon bands and surface-enhanced Raman bands of single Ag nanoparticles
    Itoh, T
    Hashimoto, K
    Ozaki, Y
    [J]. APPLIED PHYSICS LETTERS, 2003, 83 (11) : 2274 - 2276
  • [7] ITOH T, 2008, FRONTIER MOL SPECTRO, pCH10
  • [8] Second enhancement in surface-enhanced resonance Raman scattering revealed by an analysis of anti-Stokes and Stokes Raman spectra
    Itoh, Tamitake
    Yoshida, Kenichi
    Biju, Vasudevanpillai
    Kikkawa, Yasuo
    Ishikawa, Mitsuru
    Ozaki, Yukihiro
    [J]. PHYSICAL REVIEW B, 2007, 76 (08)
  • [9] Variations in steady-state and time-resolved background luminescence from surface-enhanced resonance Raman scattering-active single Ag nanoaggregates
    Itoh, Tamitake
    Kikkawa, Yasuo
    Biju, Vasudevanpillai
    Ishikawa, Mitsuru
    Ikehata, Akifumi
    Ozaki, Yukihiro
    [J]. JOURNAL OF PHYSICAL CHEMISTRY B, 2006, 110 (43): : 21536 - 21544
  • [10] Elucidation of interaction between metal-free tetraphenylporphine and surface Ag atoms through temporal fluctuation of surface-enhanced resonance Raman scattering and background-light emission
    Itoh, Tamitake
    Hashimoto, Kazuhiro
    Biju, Vasudevanpillai
    Ishikawa, Mitsuru
    Wood, Bayden R.
    Ozaki, Yukihiro
    [J]. JOURNAL OF PHYSICAL CHEMISTRY B, 2006, 110 (19): : 9579 - 9585
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