Ibrutinib in Combination with Venetoclax Decreases Mitochondrial Bioenergetics through the Impaired BTK, AKT and AMPK/SIRT/PGC-1α Signaling Pathway in CLL

被引:1
|
作者
Chowdhury, Subir Roy [1 ]
Singh, Amandeep [1 ]
Nguyen, Edwin [2 ]
Marshall, Aaron [3 ]
Johnston, James B. [4 ]
Gibson, Spencer Bruce [4 ]
Banerji, Versha [5 ,6 ]
机构
[1] CancerCare Manitoba, Res Inst Oncol & Hematol, Winnipeg, MB, Canada
[2] Univ Manitoba, CancerCare Manitoba, Winnipeg, MB, Canada
[3] Univ Manitoba, Immunol, Winnipeg, MB, Canada
[4] Canc Care Manitoba, Winnipeg, MB, Canada
[5] Univ Manitoba, Internal Med, Winnipeg, MB, Canada
[6] Univ Manitoba, Biochem & Med Genet, Winnipeg, MB, Canada
关键词
D O I
10.1182/blood-2019-127562
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1282
引用
收藏
页数:3
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