First Clinical Cases of OXA-48-Producing Carbapenem-Resistant Klebsiella pneumoniae in the United States: the "Menace" Arrives in the New World

被引：82
|
作者：
Mathers, Amy J. [1 ,2 ]
Hazen, Kevin C. [2 ,3 ]
Carroll, Joanne [2 ]
Yeh, Anthony J. [1 ]
Cox, Heather L. [1 ]
Bonomo, Robert A. [4 ,5 ]
Sifri, Costi D. [1 ,6 ]
机构：
[1] Univ Virginia Hlth Syst, Dept Med, Div Infect Dis & Int Hlth, Charlottesville, VA USA
[2] Univ Virginia Hlth Syst, Dept Pathol, Charlottesville, VA USA
[3] Duke Univ Hlth Syst, Dept Pathol, Durham, NC USA
[4] Vet Affairs Med Ctr, Louis Stokes Cleveland Dept, Res Serv, Cleveland, OH USA
[5] Vet Affairs Med Ctr, Louis Stokes Cleveland Dept, Infect Dis Sect, Cleveland, OH USA
[6] Univ Virginia Hlth Syst, Off Hosp Epidemiol, Charlottesville, VA USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2013年 / 51卷 / 02期
基金：
美国国家卫生研究院;
关键词：
BETA-LACTAMASES; SPREAD;
D O I：
10.1128/JCM.02580-12
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
OXA-48 has emerged as a major carbapenemase associated with the Enterobacteriaceae in Europe, North Africa, and Asia. We report the first two clinical cases of OXA-48-type carbapenemase-producing Enterobacteriaceae in the United States from patients recently hospitalized in Saudi Arabia and India. Each is more carbapenem resistant than nearly all previously reported OXA-48-type-producing Enterobacteriaceae.
引用
收藏
页码：680 / 683
页数：4
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