Clinical combination of the MEK inhibitor GDC-0973 and the PI3K inhibitor GDC-0941: A first-in-human phase Ib study testing daily and intermittent dosing schedules in patients with advanced solid tumors.

被引:17
|
作者
Shapiro, G.
LoRusso, P.
Kwak, E. L.
Cleary, J. M.
Musib, L.
Jones, C.
de Crespigny, A.
Belvin, M.
McKenzie, M.
Gates, M. R.
Chan, I. T.
Bendell, J. C.
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Karmanos Canc Inst, Detroit, MI USA
[3] Massachusetts Gen Hosp, Div Hematol & Oncol, Boston, MA 02114 USA
[4] Harvard Univ, Sch Med, Boston, MA USA
[5] Genentech Inc, San Francisco, CA 94080 USA
[6] Sarah Cannon Res Inst, Nashville, TN USA
关键词
D O I
10.1200/jco.2011.29.15_suppl.3005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3005
引用
收藏
页数:1
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