Progress towards a semiconductor Compton camera for prompt gamma imaging during proton beam therapy for range and dose verification

被引:8
|
作者
Gutierrez, A. [1 ]
Baker, C. [2 ]
Boston, H. [3 ]
Chung, S. [1 ]
Judson, D. S. [3 ]
Kacperek, A. [4 ]
Le Crom, B. [3 ]
Moss, R. [1 ]
Royle, G. [1 ]
Speller, R. [1 ]
Boston, A. J. [3 ]
机构
[1] UCL, Dept Med Phys & Biomed Engn, London WC1E 6BT, England
[2] Royal Berkshire NHS Fdn Trust, Med Phys Dept, Reading RG1 5AN, Berks, England
[3] Univ Liverpool, Dept Phys, Liverpool L69 3BX, Merseyside, England
[4] Clatterbridge Canc Ctr NHS Fdn Trust, Natl Eye Proton Therapy Ctr, Wirral CH63 4JY, Merseyside, England
来源
关键词
Compton imaging; Gamma detectors (scintillators; CZT; HPG; HgI etc); Instrumentation for hadron therapy; RADIOTHERAPY; SIMULATION; MODELS; SYSTEM;
D O I
10.1088/1748-0221/13/01/C01036
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
The main objective of this work is to test a new semiconductor Compton camera for prompt gamma imaging. Our device is composed of three active layers: a Si(Li) detector as a scatterer and two high purity Germanium detectors as absorbers of high-energy gamma rays. We performed Monte Carlo simulations using the Geant4 toolkit to characterise the expected gamma field during proton beam therapy and have made experimental measurements of the gamma spectrum with a 60 MeV passive scattering beam irradiating a phantom. In this proceeding, we describe the status of the Compton camera and present the first preliminary measurements with radioactive sources and their corresponding reconstructed images.
引用
收藏
页数:10
相关论文
共 50 条
  • [1] Use of a LYSO-based Compton camera for prompt gamma range verification in proton therapy
    Jan, Meei-Ling
    Hsiao, Ing-Tsung
    Huang, Hsuan-Ming
    [J]. MEDICAL PHYSICS, 2017, 44 (12) : 6261 - 6269
  • [2] Imaging of Prompt Gamma Rays Emitted During Delivery of Clinical Proton Beams with a Compton Camera: Feasibility Studies for Range Verification
    Polf, J.
    Avery, S.
    Mackin, D.
    Beddar, S.
    [J]. MEDICAL PHYSICS, 2015, 42 (06) : 3679 - 3679
  • [3] Imaging of prompt gamma rays emitted during delivery of clinical proton beams with a Compton camera: feasibility studies for range verification
    Polf, Jerimy C.
    Avery, Stephen
    Mackin, Dennis S.
    Beddar, Sam
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2015, 60 (18): : 7085 - 7099
  • [4] Prompt Gamma Imaging for In Vivo Range Verification of Pencil Beam Scanning Proton Therapy
    Xie, Yunhe
    Bentefour, El Hassane
    Janssens, Guillaume
    Smeets, Julien
    Vander Stappen, Francois
    Hotoiu, Lucian
    Yin, Lingshu
    Dolney, Derek
    Avery, Stephen
    O'Grady, Fionnbarr
    Prieels, Damien
    McDonough, James
    Solberg, Timothy D.
    Lustig, Robert A.
    Lin, Alexander
    Teo, Boon-Keng K.
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2017, 99 (01): : 210 - 218
  • [5] Noise evaluation of prompt-gamma technique for proton-therapy range verification using a Compton Camera
    Ortega, P. G.
    Torres-Espallardo, I.
    Boehlen, T. T.
    Cerutti, F.
    Chin, M. P. W.
    Ferrari, A.
    Gillam, J. E.
    Lacasta, C.
    Llosa, G.
    Oliver, J.
    Rafecas, M.
    Sala, P. R.
    Solevi, P.
    [J]. 2013 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (NSS/MIC), 2013,
  • [6] Prompt Gamma Imaging of a Pencil Beam with a High Efficiency Compton Camera at a Clinical Proton Therapy Facility
    Hueso-Gonzalez, F.
    Petzoldt, J.
    Roemer, K. E.
    Schoene, S.
    Fiedler, F.
    Golnik, C.
    Kormoll, T.
    Pausch, G.
    Enghardt, W.
    [J]. 2015 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (NSS/MIC), 2015,
  • [7] Comment on 'Imaging of prompt gamma rays emitted during delivery of clinical proton beams with a Compton camera: feasibility studies for range verification'
    Sitek, Arkadiusz
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2016, 61 (24): : 8941 - 8944
  • [8] Evaluation of a stochastic reconstruction algorithm for use in Compton camera imaging and beam range verification from secondary gamma emission during proton therapy
    Mackin, Dennis
    Peterson, Steve
    Beddar, Sam
    Polf, Jerimy
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2012, 57 (11): : 3537 - 3553
  • [9] Evaluating a Stochastic Reconstruction Algorithm for Compton Camera Based Prompt Gamma Imaging during Proton Therapy
    Mackin, D.
    Polf, J.
    Peterson, S.
    Gillin, M.
    Beddar, S.
    [J]. MEDICAL PHYSICS, 2011, 38 (06)
  • [10] Comparison of Prompt Gamma and PET Imaging for Range Verification in Proton Therapy
    Moteabbed, M.
    Espana, S.
    Paganetti, H.
    [J]. MEDICAL PHYSICS, 2011, 38 (06)