Fibromyalgia and Fatigue: Central Processing, Widespread Dysfunction

被引：14
|
作者：
Finan, Patrick H. [1 ]
Zautra, Alex J. [1 ]
机构：
[1] Arizona State Univ, Dept Psychol, Tempe, AZ 85287 USA
来源：
PM&R | 2010年 / 2卷 / 05期
关键词：
POSTTRAUMATIC-STRESS-DISORDER; PITUITARY-ADRENAL AXIS; QUALITY-OF-LIFE; RHEUMATOID-ARTHRITIS; CHRONIC PAIN; FIBROSITIS SYNDROME; POSITIVE AFFECT; TENDER POINTS; SUBSTANCE-P; ALPHA SLEEP;
D O I：
10.1016/j.pmrj.2010.03.021
中图分类号：
R49 [康复医学];
学科分类号：
100215 ;
摘要：
Biological and psychological bases for the covariation of pain and fatigue in fibromyalgia (FM) are reviewed. FM is characterized as a disorder of central sensitization, with pain and fatigue as the most prominent symptoms. The roles of sleep disturbance and affective dysregulation as both precipitants and consequences of pain and fatigue in FM are discussed. It is argued that a positive affective disturbance may uniquely characterize pain and fatigue symptoms in FM. Finally, pharmacological and nonpharmacological treatments for FM are highlighted, with an emphasis on the efficacy of these treatments in alleviating pain and fatigue symptoms. PM R 2010;2:431-437
引用
收藏
页码：431 / 437
页数：7
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