Treatment of pulmonary neuroendocrine tumours: State of the art and future developments

被引：49

作者：

Gridelli, Cesare ^{[1
]}

Rossi, Antonio ^{[1
]}

Airoma, Giuseppe ^{[2
]}

Bianco, Roberto ^{[3
]}

Costanzo, Raffaele ^{[4
]}

Daniele, Bruno ^{[5
]}

De Chiara, Giovanni ^{[6
]}

Grimaldi, Giuseppe ^{[7
]}

Irtelli, Luciana ^{[8
]}

Maione, Paolo ^{[1
]}

Morabito, Alessandro ^{[4
]}

Piantedosi, Franco Vito ^{[9
]}

Riccardi, Ferdinando ^{[10
]}

机构：

[1] SG Moscati Hosp, Div Med Oncol, I-83100 Avellino, Italy

[2] ASL NA1, Dept Oncol, Naples, Italy

[3] Univ Naples Federico II, Dept Endocrinol & Clin & Mol Oncol, Naples, Italy

[4] Natl Canc Inst, Div Thoracopulm Med Oncol, Naples, Italy

[5] G Rummo Hosp, Div Med Oncol, Benevento, Italy

[6] SG Moscati Hosp, Pathol Unit, I-83100 Avellino, Italy

[7] Umberto I Hosp, Div Oncol, Nocera Inferiore, SA, Italy

[8] SS Annunziata Hosp, Div Med Oncol, Chieti, Italy

[9] Monaldi Hosp, UOSD Day Hosp Pulm Oncol, Naples, Italy

[10] Antonio Cardarelli Hosp, Div Oncol, Naples, Italy

来源：

CANCER TREATMENT REVIEWS | 2013年 / 39卷 / 05期

关键词：

Pulmonary neuroendocrine tumours; Lung cancer; Large cell neuroendocrine carcinoma; Carcinoids; Somatostatin analogues therapy; Targeted therapy; ENDOTHELIAL GROWTH-FACTOR; CARCINOID-TUMORS; LUNG-CANCER; SOMATOSTATIN RECEPTORS; BRONCHIAL CARCINOIDS; SURGICAL-MANAGEMENT; PROGNOSTIC-FACTORS; INTERFERON-ALPHA; OCTREOTIDE; EXPRESSION;

D O I：

10.1016/j.ctrv.2012.06.012

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The current classification of pulmonary neuroendocrine tumours includes four subtypes: low-grade typical carcinoid tumour (TC), intermediate-grade atypical carcinoid tumour (AC), and two high-grade malignancies: large cell neuroendocrine carcinoma and small cell lung cancer (SCLC). Unfortunately, with the exclusion of SCLC, no large phase II and III trials for pulmonary neuroendocrine tumours have been published. Thus, several treatment approaches are available for their treatment but none of them has been validated in appropriately designed and adequately sized clinical trials. The main problem of the published studies is that they include neuroendocrine tumours from various sites of origin with different clinical behaviour. It is important that future studies consider these tumours separately. In this regard, increased awareness and referral of these patients to tertiary centres, in which a multidisciplinary management is available, may be of value. The aim of this review is to evaluate the state of the art and discuss future developments in the management of pulmonary neuroendocrine tumours excluding SCLC which we consider should be addressed in a different issue. (c) 2012 Elsevier Ltd. All rights reserved.

引用

页码：466 / 472

页数：7

共 50 条

[1] Diagnosis and treatment of bronchopulmonary neuroendocrine tumours: State of the art
Tabaksblat, Elizaveta Mitkina
Langer, Seppo W.
Knigge, Ulrich
Gronbaek, Henning
Mortensen, Jann
Petersen, Rene Horsleben
Federspiel, Birgitte Hartnack
Ladekarl, Morten
[J]. ACTA ONCOLOGICA, 2016, 55 (01) : 3 - 14
[2] State of the art and future directions in the systemic treatment of neuroendocrine neoplasms
Jungels, Christiane
Deleporte, Amelie
[J]. CURRENT OPINION IN ONCOLOGY, 2021, 33 (04) : 378 - 385
[3] Multifocal Pulmonary Neuroendocrine Tumours: Genesis, Diagnostics and Treatment
Kirschbaum, A.
Beutel, B.
Rinke, A.
Rexin, P.
Fink, L.
Koczulla, R.
Bartsch, D. K.
[J]. PNEUMOLOGIE, 2016, 70 (02): : 123 - 129
[4] STATE OF THE ART IN THE TREATMENT OF OROPHARYNX TUMOURS
Grau, C.
[J]. RADIOTHERAPY AND ONCOLOGY, 2011, 98 : S15 - S15
[5] STATE OF THE ART IN THE TREATMENT OF LARYNX TUMOURS
Guigay, J.
[J]. RADIOTHERAPY AND ONCOLOGY, 2011, 98 : S15 - S15
[6] HPV vaccination: state of the art and future developments
Chizzolini, M.
[J]. GIORNALE ITALIANO DI OSTETRICIA E GINECOLOGIA, 2008, 30 (11-12): : 359 - 361
[7] Teleservice - State-of-the-art and future developments
Hudetz, W
[J]. IECON '98 - PROCEEDINGS OF THE 24TH ANNUAL CONFERENCE OF THE IEEE INDUSTRIAL ELECTRONICS SOCIETY, VOLS 1-4, 1998, : 2103 - 2107
[8] CT angiography: State of the art and future developments
Faranna, V
[J]. RIVISTA DI NEURORADIOLOGIA, 1997, 10 : 79 - 81
[9] Plant Analysis - State of the Art and Future Developments
Ganzera, Markus
Sturm, Sonja
Stuppner, Hermann
[J]. PLANTA MEDICA, 2009, 75 (07) : 671 - 671
[10] LHe flowmeters: State of the art and future developments
Rivetti, A
Martini, G
Birello, G
[J]. ADVANCES IN CRYOGENIC ENGINEERING, VOL 41, PTS A AND B, 1996, : 1789 - 1796

← 1 2 3 4 5 →