Polymorphism of the IL-10 gene is associated with susceptibility to herpes zoster

被引：50

作者：

Haanpää, M

Nurmikko, T

Hurme, M

机构：

[1] Univ Tampere, Sch Med, Dept Microbiol & Immunol, FIN-33101 Tampere, Finland

[2] Tampere Univ Hosp, Dept Neurol & Rehabil, Tampere, Finland

[3] Univ Liverpool, Dept Neurol Sci, Pain Res Inst, Liverpool L69 3BX, Merseyside, England

来源：

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | 2002年 / 34卷 / 02期

关键词：

D O I：

10.1080/00365540110077218

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Herpes zoster (HZ) is induced by diseases or medical treatments leading to a decrease in cell-mediated immunity but in most cases it appears without any detectable, predisposing condition. We report here that susceptibility to HZ is genetically determined. The promoter region of the IL-10 gene contains 3 single-nucleotide polymorphisms (G/A at - 1082, C/T at - 819 and C/A at - 592) which form 3 haplotypes, GCC, ACC and ATA. These haplotypes are known to differ in terms of their effect on the transcription of the IL-10 gene. In a cohort of 60 HZV patients, the number of carriers of the ATA haplotype was 32 (53%), while in blood donors the frequency was 151/400 (38%) (p < 0.05).

引用

页码：112 / 114

页数：3

共 50 条

[1] Polymorphism of the IL-10 gene is associated with susceptibility to herpes zoster in Korea
Cho, Jae-We
Shin, Dong-Hoon
Lee, Kyu-Suk
[J]. JOURNAL OF DERMATOLOGICAL SCIENCE, 2007, 45 (03) : 213 - 215
[2] Functional IL-10 Gene Polymorphism Is Associated with Chagas Disease Cardiomyopathy
Costa, Germano C.
da Costa Rocha, Manoel Otavio
Moreira, Paula Rocha
Silva Menezes, Cristiane Alves
Silva, Micena R.
Gollob, Kenneth J.
Dutra, Walderez O.
[J]. JOURNAL OF INFECTIOUS DISEASES, 2009, 199 (03): : 451 - 454
[3] Interleukin-10 (IL-10) gene polymorphism as a potential host susceptibility factor in tuberculosis
Oral, Haluk B.
Budak, Ferah
Uzaslan, Esra Kunt
Basturk, Bilkay
Bekar, Ahmet
Akalin, Halls
Ege, Ercument
Ener, Beyza
Goral, Guher
[J]. CYTOKINE, 2006, 35 (3-4) : 143 - 147
[4] IL-10 gene polymorphism in diabetic retinopathy
Shi, Y-L
Shi, M-Y
Yin, L-Z
Shang, J-M
Zhuang, J-Y
[J]. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2019, 23 (12) : 5059 - 5064
[5] Pityriasis Versicolor: host susceptibility in relation to IL-10 and IFN ? cytokine gene polymorphism
Jain, Charu
Das, Shukla
Ramachandran, Vishnampettai G.
Saha, Rumpa
Bhattacharyak, Sambit Nath
Dar, Sajad Ahmad
Birhman, Nikita
Singh, Narendra Pal
[J]. HEALTHCARE IN LOW-RESOURCE SETTINGS, 2023, 11 (01)
[6] GENE POLYMORPHISM OF IL-1B AND IL-10
Zvenigorodska, Anna
Dudnyk, Veronica
[J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2017, 32 : 748 - 748
[7] The IL-10 -819T polymorphism is associated with increased susceptibility to severe sepsis
KA Wood
JA Kellum
R Ferrell
VC Arena
RL Delude
DC Angus
[J]. Critical Care, 7 (Suppl 2):
[8] Is the Polymorphism at Position-1082 of IL-10 Gene Associated with Visceral Leishmaniasis?
Hajilooi, Mehrdad
Ahmadi, Alireza
Lotfi, Pegah
Matini, Mohammad
Jafari, Davood
Bazmani, Ahad
Momeni, Mohammad
[J]. IRANIAN JOURNAL OF PUBLIC HEALTH, 2014, 43 (08) : 1107 - 1112
[9] Polymorphism of the IL-10 gene in Azeri population of Iran
Mohammad Asgharzadeh
Zahra Taghinejad
Vahid Asgharzadeh
Bahareh Mehramouz
Jalil Rashedi
Behroz Mahdavipoor
Mahya Pourostadi
Ali Vegari
Ali Safarzad Vishkaei
Sepehr Taghizadeh
Hossein Samadi Kafil
[J]. Egyptian Journal of Medical Human Genetics, 23
[10] Polymorphism of the IL-10 gene in Azeri population of Iran
Asgharzadeh, Mohammad
Taghinejad, Zahra
Asgharzadeh, Vahid
Mehramouz, Bahareh
Rashedi, Jalil
Mahdavipoor, Behroz
Pourostadi, Mahya
Vegari, Ali
Vishkaei, Ali Safarzad
Taghizadeh, Sepehr
Kafil, Hossein Samadi
[J]. EGYPTIAN JOURNAL OF MEDICAL HUMAN GENETICS, 2022, 23 (01)

← 1 2 3 4 5 →