Repeat traumatic brain injury in the developing brain

被引:52
|
作者
Prins, M. L. [1 ]
Giza, C. C. [1 ,2 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Neurosurg, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Mattel Childrens Hosp, Div Pediat Neurol, Los Angeles, CA 90095 USA
关键词
Repeat traumatic brain injury; Pediatric; Vulnerability; Experimental models; SHAKEN BABY SYNDROME; PROFESSIONAL FOOTBALL PLAYERS; REPETITIVE HEAD-INJURY; INFANT RAT MODEL; HIGH-SCHOOL; RECURRENT CONCUSSION; AXONAL INJURY; NEONATAL PIG; GRAY-MATTER; ADULT-RAT;
D O I
10.1016/j.ijdevneu.2011.05.009
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The Center for Disease Control estimates that there are 1.7 million brain injuries in the US each year with 51% of these injuries occurring during periods of cerebral development. Among this population there is a growing population of individuals with repeat traumatic brain injury (RTBI). While the exact incidence is unknown, estimates range from 5.6 to 36% of the TBI population. This review summarizes the clinical problems/challenges and experimental research models that currently exist. It is intended to reveal the critical areas that need to be addressed so that age-relevant clinical management guidelines can be established to protect this population. Published by Elsevier Ltd on behalf of ISDN.
引用
收藏
页码:185 / 190
页数:6
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