Relation of plasma brain and atrial natriuretic peptides to left ventricular geometric patterns in essential hypertension

被引：52
|
作者：
Yasumoto, K [1 ]
Takata, M [1 ]
Ueno, H [1 ]
Tomita, S [1 ]
Tomoda, F [1 ]
Inoue, H [1 ]
机构：
[1] Toyama Med & Pharmaceut Univ, Dept Internal Med 2, Toyama 9300194, Japan
来源：
AMERICAN JOURNAL OF HYPERTENSION | 1999年 / 12卷 / 09期
关键词：
natriuretic peptides; essential hypertension; left ventricular hypertrophy; left ventricular geometry;
D O I：
10.1016/S0895-7061(99)00062-X
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
We investigated whether plasma brain and atrial natriuretic peptide (BNP and ANP, respectively) levels could reflect left ventricular (LV) geometry and function in patients with mild to moderate essential hypertension. A positive correlation was found between LV mass index (LVMI) and plasma ANP levels in 84 untreated, hypertensive patients, but not between LVMI and plasma BNP levels. As compared with other geometric patterns, plasma BNP levels were increased in concentric hypertrophy, in which LVMI was increased and LV diastolic function was decreased. These data suggest that production of BNP was increased in hypertensive patients with concentric hypertrophy via LV overload or depression of diastolic function. Am J Hypertens 1999;12:921-924 (C) 1999 American Journal of Hypertension, Ltd.
引用
收藏
页码：921 / 924
页数：4
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