Overall survival (OS) of maintenance pemetrexed (pem) plus best supportive care (BSC) versus placebo plus BSC immediately following induction treatment with pem plus cisplatin for advanced nonsquamous non-small cell lung cancer (NSCLC): final results of a phase Ill study (PARAMOUNT)

被引：0

作者：

Laack, E. ^{[1
]}

Reck, M. ^{[2
]}

Schumann, C. ^{[3
]}

Eschbach, C. ^{[4
]}

Kimmich, M. ^{[5
]}

Brandts, C. ^{[6
]}

Paz-Ares, L. G. ^{[7
]}

De Marinis, F. ^{[8
]}

Dediu, M. ^{[9
]}

Pujol, J.-L. ^{[10
]}

Bidoli, P. ^{[11
]}

Molinier, O. ^{[12
]}

Sahoo, T. P. ^{[13
]}

Corral, J. ^{[14
]}

Melemed, S. A. ^{[14
]}

John, W. J. ^{[14
]}

Chouaki, N. ^{[15
]}

Zimmermann, A. H. ^{[14
]}

Visseren-Grul, C. M. ^{[16
]}

Leschinger, M., I ^{[17
]}

Thomas, M. ^{[18
]}

机构：

[1] Ambulantes Krebszentrum, Hamburg, Germany

[2] Krankenhaus Grosshansdorf, Grosshansdorf, Germany

[3] Univ Ulm Klinikum, Sekt Pneumol, Ulm, Germany

[4] Asklepios Klin Hamburg, Hamburg, Germany

[5] Klin Schillerhohe, Gerlingen, Germany

[6] Uniklin, Frankfurt, Germany

[7] Hosp Univ Virgen del Rocio, Seville, Spain

[8] San Camillo Forlanini Hosp, Rome, Italy

[9] Inst Oncol Bucharest, Bucharest, Romania

[10] Montpellier Univ Hosp, Montpellier, France

[11] Az Osped S Gerardo, Monza, Italy

[12] Les Mans Reg Hosp, Le Mans, France

[13] Jawaharlal Nehru Canc Hosp & Res Ctr, Bhopal, India

[14] Eli Lilly & Co, Indianapolis, IN 46285 USA

[15] Lilly France, Suresnes, France

[16] Lilly Oncol Europe, Houten, Netherlands

[17] Lilly Deutschland GmbH, Med, Oncol, Bad Homburg, Germany

[18] Univ Heidelberg, Thoraxklin, Heidelberg, Germany

来源：

ONKOLOGIE | 2012年 / 35卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：36 / 37

页数：2

共 50 条

[1] PARAMOUNT: Phase III study of maintenance pemetrexed (pem) plus best supportive care (BSC) versus placebo plus BSC immediately following induction treatment with pem plus cisplatin for advanced nonsquamous non-small cell lung cancer (NSCLC)
Paz-Ares, L. G.
De Marinis, F.
Dediu, M.
Thomas, M.
Pujol, J.
Bidoli, P.
Molinier, O.
Sahoo, T. P.
Laack, E.
Reck, M.
Corral, J.
Melemed, S. A.
John, W. J.
Chouaki, N.
Zimmerman, A.
Grul, C. M. Visseren
Gridelli, C.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
[2] PARAMOUNT: Phase III study of maintenance pemetrexed (pem) plus best supportive care (BSC) versus placebo plus BSC immediately following induction treatment with pem plus cisplatin for advanced nonsquamous non-small cell lung cancer (NSCLC)
Paz-Ares, L. G.
De Marinis, F.
Dediu, M.
Thomas, M.
Pujol, J.
Bidoli, P.
Molinier, O.
Sahoo, T. P.
Laack, E.
Reck, M.
Corral, J.
Melem, S. A.
Grul, C. M. Visseren
Gridelli, C.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (18)
[3] PARAMOUNT: Final overall survival (OS) results of the phase III study of maintenance pemetrexed (pem) plus best supportive care (BSC) versus placebo (plb) plus BSC immediately following induction treatment with pem plus cisplatin (cis) for advanced nonsquamous (NS) non-small cell lung cancer (NSCLC).
Paz-Ares, Luis
De Marinis, Filippo
Dediu, Mircea
Thomas, Michael
Pujol, Jean-Louis
Bidoli, Paolo
Molinier, Oliver
Sahoo, Tarini Prasad
Laack, Eckart
Reck, Martin
Jaime, Jesus Corral
Melemed, Symantha
John, William J.
Chouaki, Nadia
Zimmermann, Annamaria
Visseren-Grul, Carla
Gridelli, Cesare
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
[4] MAINTENANCE PEMETREXED (PEM) PLUS BEST SUPPORTIVE CARE (BSC) VERSUS PLACEBO PLUS BSC AFTER PEM PLUS CISPLATIN FOR ADVANCED NONSQUAMOUS NSCLC
Obasaju, C. K.
Paz-Ares, L. G.
De Marinis, F.
Dediu, M.
Thomas, M.
Pujol, J. L.
Bidoli, P.
Molinier, O.
Sahoo, T. P.
Laack, E.
Reck, M.
Corral, J.
Melemed, S. A.
John, W. J.
Chouaki, N.
Zimmermann, A.
Visseren-Grul, C. M.
Gridelli, C.
[J]. ANNALS OF ONCOLOGY, 2012, 23 : 8 - 8
[5] UPDATED SAFETY AND QUALITY OF LIFE (QOL) RESULTS OF PARAMOUNT STUDY: MAINTENANCE PEMETREXED (PEM) PLUS BEST SUPPORTIVE CARE (BSC) VS PLACEBO (PBO) PLUS BSC IMMEDIATELY FOLLOWING INDUCTION TREATMENT WITH PEM PLUS CISPLATIN (CP) FOR ADVANCED NONSQUAMOUS NON-SMALL CELL LUNG CANCER (NS-NSCLC)
Pujol, J.
Paz-Ares, L.
Dediu, M.
Thomas, M.
Bidoli, P.
Corral, J.
Chouaki, N.
Visseren-Grul, C. M.
Zimmermann, A.
Gridelli, C.
[J]. ANNALS OF ONCOLOGY, 2012, 23 : 418 - 419
[6] Maintenance pemetrexed (Pem) plus best supportive care (BSC) versus placebo (Plac) plus BSC: A randomized phase III study in advanced non-small cell lung cancer (NSCLC)
Belani, C. P.
Brodowicz, T.
Ciuleanu, T.
Kim, J. H.
Krzakowski, M.
Laack, E.
Wu, Y. L.
Peterson, P.
Krejcy, K.
Zielinski, C.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (18)
[7] Maintenance pemetrexed (Pem) plus best supportive care (BSC) versus placebo (Plac) plus BSC: A randomized phase III study in advanced non-small cell lung cancer (NSCLC)
Belani, C. P.
Brodowicz, T.
Ciuleanu, T.
Kim, J. H.
Krzakowski, M.
Laack, E.
Wu, Y. L.
Peterson, P.
Krejcy, K.
Zielinski, C.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
[8] A RANDOMIZED PHASE 2 STUDY COMPARING MAINTENANCE PEMETREXED (PEM) PLUS BEST SUPPORTIVE CARE (BSC) VERSUS BSC ALONE FOLLOWING INDUCTION TREATMENT WITH PEM-CISPLATIN (CIS) IN ADVANCED NONSQUAMOUS (NONSQ) NON-SMALL CELL LUNG CANCER (NSCLC)
Meshref, Mohamed
Gaafar, Rabab M.
Shehata, Samir
Hashem, Tarek
Gerges, Dani Abi
Azim, Hamdy Abdel
El-Husseiny, Gamal
Al-Hussein, Hamed
Liu, Zhixin
[J]. JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (06) : S1263 - S1263
[9] SAFETY, RESOURCE USE, AND QUALITY OF LIFE (QOL) RESULTS FROM PARAMOUNT: A PHASE III STUDY OF MAINTENANCE PEMETREXED PLUS BEST SUPPORTIVE CARE (BSC) VERSUS PLACEBO PLUS BSC IMMEDIATELY FOLLOWING INDUCTION TREATMENT WITH PEMETREXED-CISPLATIN FOR ADVANCED NONSQUAMOUS NON-SMALL CELL LUNG CANCER (NSCLC)
Gridelli, Cesare
De Marinis, Filippo
Pujol, Jean-Louis
Reck, Martin
Ramlau, Rodryg
Parente, Barbara
Pieters, Thierry
Middleton, Gary
Winfree, Katherine
Melemed, Symantha
Zimmermann, Annamaria H.
John, William
Beyrer, Julie
Chouaki, Nadia
Visseren-Grul, Carla
Paz Ares, Luis
[J]. JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (06) : S323 - S324
[10] PARAMOUNT: DESCRIPTIVE SUBGROUP ANALYSES OF FINAL OVERALL SURVIVAL (OS) FOR THE PHASE III STUDY OF MAINTENANCE PEMETREXED (PEM) VERSUS PLACEBO (PLB) FOLLOWING INDUCTION TREATMENT WITH PEM PLUS CISPLATIN (CIS) FOR ADVANCED NONSQUAMOUS (NS) NON-SMALL CELL LUNG CANCER (NSCLC)
Reck, M.
Paz-Ares, L.
De Marinis, F.
Molinier, O.
Sahoo, T. Prasad
Laack, E.
John, W.
Zimmermann, A.
Visseren-Grul, C. M.
Gridelli, C.
[J]. ANNALS OF ONCOLOGY, 2012, 23 : 404 - 404

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