NEUTRON IMAGING IN A HOSPITAL ENVIRONMENT

被引：0

作者：

Scazzi, S. ^{[1
]}

Bolognini, D. ^{[1
]}

Mascagna, V. ^{[1
]}

Mattera, A. ^{[1
]}

Prest, M. ^{[1
]}

Bartesaghi, G. ^{[2
,3
]}

Conti, V. ^{[2
,3
]}

Mozzanica, A. ^{[4
,5
]}

Cappelletti, P. ^{[6
]}

Frigerio, M. ^{[6
]}

Gelosa, S. ^{[6
]}

Monti, A. ^{[6
]}

Ostinelli, A. ^{[6
]}

Giannini, G. ^{[7
,8
]}

Vallazza, E. ^{[7
,8
]}

Basilico, F. ^{[9
]}

Mauri, P. ^{[9
]}

机构：

[1] Univ Insubria Como, Como, Italy

[2] Univ Milan, Milan, Italy

[3] INFN, Milan, Italy

[4] Univ Brescia, I-25121 Brescia, Italy

[5] INFN Sez, Pavia, Italy

[6] Ospedale S Anna Como, Fis Sanitaria, Como, Italy

[7] INFN, Sez Trieste, Trieste, Italy

[8] Univ Trieste, Trieste, Italy

[9] CNR Milano, Ist Tecnol Biomed, Milan, Italy

来源：

ASTROPARTICLE, PARTICLE AND SPACE PHYSICS, DETECTORS AND MEDICAL PHYSICS APPLICATIONS | 2008年 / 4卷

关键词：

Neutron imaging; Boron concentration;

D O I：

10.1142/9789812819093_0115

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

BNCT is a technique exploiting the capture conversion process of thermal neutrons in the reaction B-10(n,alpha)Li-7 to treat extended and radioresistant tumours. One of its main limitations is the lack of specificity of the boron compounds with respect to tumour cells, which needs to be studied with a dedicated neutron beam. This work, developed within the INFN PhoNeS project and carried out at the radiotherapy unit of the S. Anna Hospital in Como with a Varian Clinac 2100C/D, describes the possibility of neutron imaging, performed with the neutrons produced by a Linac detecting the alpha particles with a non depleted self-triggering microstrip silicon detector. Several trials have been made with solutions of B-10 at different percentages, obtaining a minimum sensitivity of 1.9 nmol/cm(2). The paper describes the detector, the measurement setup and the first results with biological samples.

引用

页码：686 / +

页数：4

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