New models for the action of some type2-cytokines (IL4/IL13 and IL10), based on the postulated increased H2O2-level in Th1 vs. Th2 cells: (1) IL4 and IL13 act, in contrast to type 1-cytokines (IFNgamma), (a) by upregulation of catalase/glutathione peroxide and/or (b) by downregulation of superoxide dismutase(s). (2) One of IL-10 actions is inhibition of cAMP-PDE(s).

被引：0

作者：

Leskovar, P ^{[1
]}

Schmidmaier, R ^{[1
]}

Dickelhuber, A ^{[1
]}

Graw, M ^{[1
]}

Abdalla, K ^{[1
]}

机构：

[1] Univ TU Munich, Sch Med, Immunol Biochem Res Lab, Munich, Germany

来源：

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D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：S20 / S20

页数：1

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