Imaging techniques: new avenues in cancer gene and cell therapy

被引:40
|
作者
Saadatpour, Z. [1 ]
Rezaei, A. [2 ]
Ebrahimnejad, H. [3 ]
Baghaei, B. [4 ]
Bjorklund, G. [5 ]
Chartrand, M. [6 ]
Sahebkar, A. [7 ]
Morovati, H. [8 ]
Mirzaei, H. R. [9 ]
Mirzaei, H. [10 ]
机构
[1] Isfahan Univ Med Sci, Bozorgmehr Imaging Ctr, Esfahan, Iran
[2] Isfahan Univ Med Sci, Khanevadeh Hosp, Esfahan, Iran
[3] Kerman Univ Med Sci, Sch Dent, Dept Oral & Maxillofacial Radiol, Kerman, Iran
[4] Rafsanjan Univ Med Sci, Sch Dent, Dept Endodont, Rafsanjan, Iran
[5] Nutr & Environm Med, Mo I Rana, Norway
[6] DigiCare Behav Res, Casa Grande, AZ USA
[7] Mashhad Univ Med Sci, Biotechnol Res Ctr, Mashhad, Iran
[8] Tabriz Univ Med Sci, Dept Med Parasitol & Med Mycol, Fac Med, Tabriz, Iran
[9] Univ Tehran Med Sci, Sch Med, Dept Immunol, Tehran, Iran
[10] Mashhad Univ Med Sci, Sch Med, Dept Med Biotechnol, Mashhad, Iran
关键词
POSITRON-EMISSION-TOMOGRAPHY; MESENCHYMAL STEM-CELL; VIRUS-THYMIDINE KINASE; PROSTATE-CANCER; T-CELLS; MAGNETIC-RESONANCE; TUMOR RESPONSE; BREAST-CANCER; TRANSGENE EXPRESSION; OVARIAN-CANCER;
D O I
10.1038/cgt.2016.61
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Canter is one of the world's most concerning health problems and poses many challenges in the range of approaches associated with the treatment of canter. Current understanding of this disease brings to the fore a number of novel therapies that can be useful in the treatment of cancer. Among them, gene and cell therapies have emerged as novel and effective approaches. One of the most important challenges for cancer gene and cell therapies is correct monitoring of the modified genes and cells. In fact, visual tracking of therapeutic cells, immune cells, stem cells and genetic vectors that contain therapeutic genes and the various drugs is important in cancer therapy. Similarly, molecular imaging, such as nanosystems, fluorescence, bioluminescence, positron emission tomography, single photon-emission computed tomography and magnetic resonance imaging, have also been found to be powerful tools in monitoring cancer patients who have received therapeutic cell and gene therapies or drug therapies. In this review, we focus on these therapies and their molecular imaging techniques in treating and monitoring the progress of the therapies on various types of cancer.
引用
收藏
页码:1 / 5
页数:5
相关论文
共 50 条
  • [1] Imaging techniques: new avenues in cancer gene and cell therapy
    Z Saadatpour
    A Rezaei
    H Ebrahimnejad
    B Baghaei
    G Bjorklund
    M Chartrand
    A Sahebkar
    H Morovati
    H R Mirzaei
    H Mirzaei
    [J]. Cancer Gene Therapy, 2017, 24 : 1 - 5
  • [2] Biopharmaceuticals and gene vectors opening new avenues in cancer immune therapy
    Sami, Haider
    Ogris, Manfred
    [J]. THERAPEUTIC DELIVERY, 2016, 7 (07) : 419 - 422
  • [3] Liver repopulation with hepatocyte transplantation: New avenues for gene and cell therapy
    Gupta, S
    Malhi, H
    Gagandeep, S
    Novikoff, P
    [J]. JOURNAL OF GENE MEDICINE, 1999, 1 (06): : 386 - 392
  • [4] Kidney cancer therapy: new perspectives and avenues
    Alexandrescu, Doru T.
    Dasanu, Constantin A.
    [J]. EXPERT OPINION ON PHARMACOTHERAPY, 2006, 7 (18) : 2481 - 2493
  • [5] New avenues in non viral gene delivery and therapy
    Bigey, Pascal
    Burgain, Aurore
    Escriou, Virginie
    Marie, Corinne
    Quiviger, Mickael
    Schlegel, Anne
    Scherman, Daniel
    [J]. HUMAN GENE THERAPY, 2012, 23 (10) : A30 - A30
  • [6] Subcellular Chemical Imaging: New Avenues in Cell Biology
    Decelle, Johan
    Veronesi, Giulia
    Gallet, Benoit
    Stryhanyuk, Hryhoriy
    Benettoni, Pietro
    Schmidt, Matthias
    Tucoulou, Remi
    Passarelli, Melissa
    Bohic, Sylvain
    Clode, Peta
    Musat, Niculina
    [J]. TRENDS IN CELL BIOLOGY, 2020, 30 (03) : 173 - 188
  • [7] Molecular diagnostics and therapy of prostate cancer: New avenues
    Schalken, J
    [J]. EUROPEAN UROLOGY, 1998, 34 : 3 - 6
  • [8] Current advances in molecular imaging of gene and cell therapy for cancer
    Shah, K
    [J]. CANCER BIOLOGY & THERAPY, 2005, 4 (05) : 518 - 523
  • [9] Nanomedicine has opened new avenues for cancer diagnosis and therapy
    Zhi-Fei Dai
    [J]. Cancer Biology & Medicine, 2016, 13 (03) : 297 - 298
  • [10] Nanomedicine has opened new avenues for cancer diagnosis and therapy
    Dai, Zhi-Fei
    [J]. CANCER BIOLOGY & MEDICINE, 2016, 13 (03) : 297 - 298