Efficacy and safety of risedronate 150 mg once a month in the treatment of postmenopausal osteoporosis

被引:0
|
作者
Rackoff, Paula [1 ]
机构
[1] Beth Israel Deaconess Med Ctr, Div Rheumatol, New York, NY 10003 USA
关键词
osteoporosis; fracture; SEE VOL. 176; HIP FRACTURE; VERTEBRAL FRACTURES; NONVERTEBRAL FRACTURES; ORAL BISPHOSPHONATES; RANDOMIZED-TRIAL; POOLED ANALYSIS; RISK-FACTORS; ELDERLY-MEN; PG; 1256;
D O I
暂无
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Fragility fractures that occur as a result of osteoporosis are frequently associated with chronic pain and decreased quality of life as well as significant morbidity and mortality. Fracture reduction, however, is often less than optimal due to poor compliance with medications. Studies have demonstrated that risedronate, a heterocyclic nitrogen containing bisphosphonate can reduce vertebral, nonvertebral, and hip fracture incidence in postmenopausal women, in men, and in subsets of older patients at great risk of falls and fragility. The mechanism, efficacy, dosing options, and tolerability of risedronate are reviewed.
引用
收藏
页码:207 / 214
页数:8
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