Thermodynamic Analysis of Allosteric and Chelate Cooperativity in Di- and Trivalent Ammonium/Crown-Ether Pseudorotaxanes

被引：23

作者：

Nowosinski, Karol ^{[1
]}

von Krbek, Larissa K. S. ^{[1
]}

Traulsen, Nora L. ^{[1
]}

Schalley, Christoph A. ^{[1
]}

机构：

[1] Free Univ Berlin, Inst Chem & Biochem, D-14195 Berlin, Germany

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 20期

关键词：

STATISTICAL FACTORS; SYMMETRY NUMBERS; MULTIVALENCY; COMPLEXATION; ORGANIZATION; CONSTANTS;

D O I：

10.1021/acs.orglett.5b02592

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A detailed thermodynamic analysis of the axle-wheel binding in di- and trivalent secondary arnmonium/[24]crown-8 pseudorotaxanes is presented. Isothermal titration calorimetry (ITC) data and double mutant cycle analyses reveal an interesting interplay of positive as well as negative allosteric and positive chelate cooperativity thus providing profound insight into the effects governing multivalent binding in these pseudorotaxanes.

引用

页码：5076 / 5079

页数：4

共 4 条

[1] Allosteric and Chelate Cooperativity in Divalent Crown Ether/Ammonium Complexes with Strong Binding Enhancement
von Krbek, Larissa K. S.
Achazi, Andreas J.
Solleder, Marthe
Weber, Marcus
Paulus, Beate
Schalley, Christoph A.
CHEMISTRY-A EUROPEAN JOURNAL, 2016, 22 (43) : 15475 - 15484
[2] Chelate cooperativity effects on the formation of di- and trivalent pseudo[2]rotaxanes with diketopiperazine threads and tetralactam wheels
Traulsen, Nora L.
Traulsen, Christoph H. -H.
Deutinger, Peter M.
Mueller, Sebastian
Schmidt, Deborah
Linder, Igor
Schalley, Christoph A.
ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, 13 (44) : 10881 - 10887
[3] Thermodynamic studies of crown-ether complexes with alkali-metal and ammonium ions in various solvents
Ohtsu, K
BUNSEKI KAGAKU, 1997, 46 (02) : 167 - 168
[4] AMMONIUM REDOX-RESPONSIVE RECEPTORS CONTAINING MULTIPLE FERROCENE AND QUINONE REDOX-ACTIVE CENTERS ATTACHED TO DI-AZA AND TRI-AZA CROWN-ETHER MACROCYCLES
BEER, PD
CROWE, DB
OGDEN, MI
DREW, MGB
MAIN, B
JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1993, (14): : 2107 - 2116

← 1 →