Off-target drug effects due to retroactivity in signaling pathways

被引：0
|
作者：
Wynn, Michelle
Ventura, Alejandra
Garcia, Hector
Merajver, Sofia
机构：
来源：
CANCER RESEARCH | 2010年 / 70卷
关键词：
D O I：
10.1158/1538-7445.AM10-2012
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2012
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Off-target drug effects due to retroactivity in signaling pathways
    Wynn, Michelle
    Ventura, Alejandra
    Garcia, Hector
    Merajver, Sofia
    CANCER RESEARCH, 2010, 70
  • [2] Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity
    Wynn, Michelle L.
    Ventura, Alejandra C.
    Sepulchre, Jacques A.
    Garcia, Hector J.
    Merajver, Sofia D.
    BMC SYSTEMS BIOLOGY, 2011, 5
  • [3] Elucidating the role of retroactive signaling and kinase inhibitors on off-target drug effects
    Wynn, Michelle L.
    Ventura, Alejandra C.
    Garcia, Hector
    Sepulchre, Jacques-A.
    Merajver, Sofia D.
    CANCER RESEARCH, 2011, 71
  • [4] Target specificity and off-target effects as determinants of cancer drug efficacy
    Shoshan, Maria C.
    Linder, Stig
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2008, 4 (03) : 273 - 280
  • [5] Predicting off-target drug interactions
    Reactions Weekly, 2012, 1415 (1) : 2 - 2
  • [6] PREDICTION OF OFF-TARGET DRUG EFFECTS THROUGH DATA FUSION
    Yera, Emmanuel R.
    Cleves, Ann E.
    Jain, Ajay N.
    PACIFIC SYMPOSIUM ON BIOCOMPUTING 2014, 2014, : 160 - 171
  • [7] Off-Target Effects of the Septin Drug Forchlorfenuron on Nonplant Eukaryotes
    Heasley, Lydia R.
    Garcia, Galo, III
    McMurray, Michael A.
    EUKARYOTIC CELL, 2014, 13 (11) : 1411 - 1420
  • [8] The zebrafish embryo as a model for assessing off-target drug effects
    Straehle, Uwe
    Grabher, Clemens
    DISEASE MODELS & MECHANISMS, 2010, 3 (11-12) : 689 - 692
  • [9] Harnessing off-target effects
    Saginc, Gaye
    Voellmy, Franziska
    Linding, Rune
    NATURE CHEMICAL BIOLOGY, 2017, 13 (12) : 1204 - +
  • [10] Off-target effects of optogenetics
    Le Bras, Alexandra
    LAB ANIMAL, 2021, 50 (11) : 308 - 308
12345