Post-stroke Movement Disorders: Clinical Manifestations and Pharmacological Management

被引:44
|
作者
Siniscalchi, Antonio [1 ]
Gallelli, Luca [2 ]
Labate, Angelo [4 ]
Malferrari, Giovanni [3 ]
Palleria, Caterina [2 ]
De Sarro, Giovambattista [2 ]
机构
[1] Annunziata Hosp, Dept Neurosci, Div Neurol, Cosenza, Italy
[2] Univ Catanzaro, Chair Pharmacol, Mater Domini Univ Hosp, Dept Hlth Sci,Sch Med,Clin Pharmacol Unit, I-88100 Catanzaro, Italy
[3] Santa Maria Nuova Hosp, Dept Neurol, Reggio Emilia, Italy
[4] Univ Catanzaro, Inst Neurol, Catanzaro, Italy
关键词
Post-stroke; movement disorders; hyperkinetic movements disorders; hypokinetic movements disorders; GABA; Dopamine; post-stroke recovery; FOCAL CEREBRAL-ISCHEMIA; PLACEBO-CONTROLLED TRIAL; ATTENUATES BRAIN-DAMAGE; ESSENTIAL TREMOR; VASCULAR PARKINSONISM; BASAL GANGLIA; THALAMIC STROKE; DOUBLE-BLIND; FUNCTIONAL REORGANIZATION; HEMICHOREA-HEMIBALLISMUS;
D O I
10.2174/157015912803217341
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Involuntary abnormal movements have been reported after ischaemic and haemorrhagic stroke. Post stroke movement disorders can appear as acute or delayed sequel. At the moment, for many of these disorders the knowledge of pharmacological treatment is still inadequate. Dopaminergic and GABAergic systems may be mainly involved in post-stroke movement disorders. This article provides a review on drugs commonly used in post-stroke movement disorders, given that some post-stroke movement disorders have shown a partial benefit with pharmacological approach.
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页码:254 / 262
页数:9
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