Periodontal Disease and Periodontal Tissue Regeneration

被引:39
|
作者
Tobita, Morikuni [1 ,2 ]
Mizuno, Hiroshi [1 ]
机构
[1] Nippon Med Sch, Dept Plast & Reconstruct Surg, Tokyo 113, Japan
[2] Minist Def, Maritime Staff Off, Off Surg Gen & Director Med, Tokyo 1628830, Japan
关键词
Adipose-derived stem cells; periodontal disease; periodontal tissue regeneration; tissue engineering; mesenchymal stem cells; fat tissue; MESENCHYMAL STEM-CELLS; PLATELET-RICH PLASMA; HUMAN ADIPOSE-TISSUE; RESPIRATORY-DISEASES; ATTACHMENT FORMATION; FURCATION DEFECTS; STROMAL CELLS; IN-VIVO; DIFFERENTIATION; LIGAMENT;
D O I
10.2174/157488810791268672
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Periodontal disease leads to destruction of the periodontium such as alveolar bone, cementum, the periodontal ligament, and gingiva. Effective treatment for periodontal tissue regeneration is important, because periodontal disease is related to several systemic diseases. However, various conventional therapies for periodontal tissue regeneration have shown limited and variable clinical outcomes. Thus, there are ongoing efforts to identify an alternative cell source, such as stem cells, for the development of new tissue engineering therapies. In this review, periodontal disease and the application of tissue engineering for periodontal tissue regeneration are discussed. In particular, adipose-derived stem cells are presented as an agent for restoring periodontal tissue defects.
引用
收藏
页码:168 / 174
页数:7
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