Platelet Transfusions in the Neonatal Intensive Care Unit

被引:21
|
作者
Sparger, Katherine [1 ]
Deschmann, Emoke [2 ]
Sola-Visner, Martha [3 ]
机构
[1] Massachusetts Gen Hosp, Dept Pediat, Boston, MA 02114 USA
[2] Karolinska Univ Hosp, Dept Neonatol, Astrid Lindgren Childrens Hosp, S-17176 Stockholm, Sweden
[3] Boston Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
关键词
Platelet transfusions; Neonatal intensive care unit; Thrombocytopenia; FUNCTION ANALYZER; CORD BLOOD; PRIMARY HEMOSTASIS; NEWBORN PLATELETS; CONTROLLED-TRIAL; REFERENCE RANGES; BLEEDING TIMES; THROMBOCYTOPENIA; CHILDREN; COUNT;
D O I
10.1016/j.clp.2015.04.009
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
There is significant world-wide variability in platelet transfusion thresholds used to transfuse thrombocytopenic neonates. A large multicenter randomized controlled trial comparing 2 different platelet transfusion thresholds in neonates is currently ongoing, and should provide data to guide transfusion practice. However, several studies have found that factors other than the degree of thrombocytopenia determine the bleeding risk. Thus, it will be important to develop better tests to assess primary hemostasis and bleeding risk in neonates.
引用
收藏
页码:613 / +
页数:12
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