The JAK-inhibitor Ruxolitinib impairs dendritic cell function in vitro and in vivo

被引：0
|
作者：
Heine, A. [1 ]
Held, S. A. E. [1 ]
Daecke, S. N. [1 ]
Wallner, S. [2 ,3 ]
Yajnanarayana, S. P. [1 ]
Kurts, C. [4 ,5 ]
Wolf, D. [1 ]
Brossart, P. [1 ]
机构：
[1] Univ Klinikum Bonn, Bonn, Germany
[2] Univ Innsbruck Hosp, Tyrolean Canc Res Inst, A-6020 Innsbruck, Austria
[3] Dept Med, Innsbruck, Austria
[4] Univ Bonn, Inst Mol Med, Bonn, Germany
[5] Univ Bonn, Inst Expt Immunol, Bonn, Germany
来源：
ONKOLOGIE | 2013年 / 36卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：215 / 216
页数：2
相关论文
共 50 条
  • [1] The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo
    Heine, Annkristin
    Held, Stefanie Andrea Erika
    Daecke, Solveig Nora
    Wallner, Stephanie
    Yajnanarayana, Sowmya Parampalli
    Kurts, Christian
    Wolf, Dominik
    Brossart, Peter
    BLOOD, 2013, 122 (07) : 1192 - 1202
  • [2] THE JAK-INHIBITOR RUXOLITINIB SUBSTANTIALLY AFFECTS NK CELL BIOLOGY
    Rudolph, J.
    Schoenberg, K.
    Cornez, I.
    Brossart, P.
    Wolf, D.
    HAEMATOLOGICA, 2014, 99 : 514 - 514
  • [3] The Pan- JAK Inhibitor Ruxolitinib Impairs T-Cell Activation, Cytokine Production and Proliferation In Vivo and In Vitro
    Stuebig, Thomas
    Wolschke, Christine
    Alchalby, Haefaa
    Ayuk, Francis
    Heinzelmann, Marion
    Triviai, Ioanna
    Badbaran, Anita
    Hildebrandt, York
    Kroeger, Nicolaus
    BLOOD, 2013, 122 (21)
  • [4] The novel JAK-inhibitor pacritinib exerts fewer immunosuppressive effects on human dendritic cells than Ruxolitinib
    Heine, A.
    Held, S. A. E.
    Daecke, S. N.
    Kampmann, S.
    Wolf, D.
    Brossart, P.
    ONCOLOGY RESEARCH AND TREATMENT, 2019, 42 : 216 - 216
  • [5] JAK-Inhibitor Ruxolitinib als zukünftige neue Behandlungsoption?
    best practice onkologie, 2011, 6 (4) : 27 - 27
  • [6] The JAK-inhibitor ruxolitinib exerts substantial impact on body weight
    Vonnahme, M.
    Trebicka, J.
    Isfort, S.
    Koschmieder, S.
    Bruemmendorf, T. H.
    Brossart, P.
    Wolf, D.
    Oncology Research and Treatment, 2015, 38 : 228 - 229
  • [7] The JAK Inhibitor Ruxolitinib Impairs Dendritic Cell Migration Via Off-Target Inhibition of Rock
    Rudolph, Janna
    Heine, Annkristin
    Quast, Thomas
    Kolanus, Waldemar
    Brossart, Peter
    Wolf, Dominik
    BLOOD, 2015, 126 (23)
  • [8] The JAK inhibitor ruxolitinib impairs dendritic cell migration via off-target inhibition of ROCK
    Rudolph, J.
    Heine, A.
    Quast, T.
    Kolanus, W.
    Trebicka, J.
    Brossart, P.
    Wolf, D.
    LEUKEMIA, 2016, 30 (10) : 2119 - 2123
  • [9] The JAK inhibitor ruxolitinib impairs dendritic cell migration via off-target inhibition of ROCK
    J Rudolph
    A Heine
    T Quast
    W Kolanus
    J Trebicka
    P Brossart
    D Wolf
    Leukemia, 2016, 30 : 2119 - 2123
  • [10] The JAK inhibitor ruxolitinib impairs dendritic cell migration via off-target inhibition of ROCK activation
    Rudolph, J.
    Heine, A.
    Quast, T.
    Kolanus, W.
    Brossart, P.
    Wolf, D.
    BONE MARROW TRANSPLANTATION, 2015, 50 : S50 - S50
12345